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Merck
CN

U0508

Sigma-Aldrich

单克隆抗-泛素 小鼠抗

clone 6C1, ascites fluid

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About This Item

MDL编号:
UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

mouse

质量水平

偶联物

unconjugated

抗体形式

ascites fluid

抗体产品类型

primary antibodies

克隆

6C1, monoclonal

包含

15 mM sodium azide

种属反应性

human, rat, mouse, bovine

技术

indirect ELISA: suitable
microarray: suitable
western blot: 1:1,000 using whole cell lysate of human promyelocitic HL60 cells

同位素/亚型

IgG2a

UniProt登记号

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

一般描述

泛素是一种大小约为8.5kD(76个氨基酸)的蛋白质,高度保守,在原核生物和真核生物中均存在。它可促进泛素/蛋白酶体途径中的蛋白质降解,并且在细胞内调节中也起关键作用。单克隆抗泛素抗体可用于免疫印迹和酶联免疫吸附测定以定位和检测泛素。小鼠抗泛素抗体在小鼠、人、牛和大鼠中可与泛素发生特异性反应。

免疫原

与KLH偶联的纯化牛泛素。

应用

单克隆抗泛素抗体可以用于蛋白印迹,以对泛素化的蛋白进行观察和评估。其也可用于微阵列和免疫印迹中。
成功使用该抗体的应用以及相关的同行评审论文如下所示。
蛋白质免疫印迹分析(1篇论文)

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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储存分类代码

10 - Combustible liquids

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

从最新的版本中选择一种:

分析证书(COA)

Lot/Batch Number

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访问文档库

Yuga Takahashi et al.
FEBS letters, 585(12), 1741-1747 (2011-05-17)
Nerve growth factor (NGF) binding to its receptor TrkA, which belongs to the family of receptor tyrosine kinases (RTKs), is known to induce its internalization, endosomal trafficking and subsequent lysosomal degradation. The Cbl family of ubiquitin ligases plays a major
Andrej Susor et al.
Reproduction (Cambridge, England), 134(4), 559-568 (2007-09-25)
In this study, we performed proteomic analysis of porcine oocytes during in vitro maturation. Comparison of oocytes at the initial and final stages of meiotic division characterized candidate proteins that were differentially synthesized during in vitro maturation. While the biosynthesis
Ana P Valencia et al.
BMC musculoskeletal disorders, 18(1), 436-436 (2017-11-11)
Rotator cuff (RTC) tears are a common clinical problem resulting in adverse changes to the muscle, but there is limited information comparing histopathology to contractile function. This study assessed supraspinatus force and susceptibility to injury in the rat model of
Mandy H Y Lam et al.
PloS one, 8(9), e75372-e75372 (2013-09-27)
The yeast HECT-family E3 ubiquitin ligase Rsp5 has been implicated in diverse cell functions. Previously, we and others [1], [2] reported the physical and functional interaction of Rsp5 with the deubiquitinating enzyme Ubp2, and the ubiquitin associated (UBA) domain-containing cofactor
Kalidou Ndiaye et al.
Journal of ovarian research, 8, 12-12 (2015-04-18)
LAPTM4B is a member of the lysosome-associated transmembrane protein superfamily that is differentially expressed in normal human tissues and upregulated in various types of carcinomas. These proteins are thought to be involved in the regulation of cell proliferation and survival.

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