产品名称
单克隆抗-泛素 小鼠抗, clone 6C1, ascites fluid
biological source
mouse
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
6C1, monoclonal
contains
15 mM sodium azide
species reactivity
human, rat, mouse, bovine
technique(s)
indirect ELISA: suitable
microarray: suitable
western blot: 1:1,000 using whole cell lysate of human promyelocitic HL60 cells
isotype
IgG2a
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... UBB(7314), UBC(7316)
mouse ... Ubb(22187), Ubc(22190)
rat ... Ubb(192255), Ubc(50522)
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
泛素是一种大小约为8.5kD（76个氨基酸）的蛋白质，高度保守，在原核生物和真核生物中均存在。它可促进泛素/蛋白酶体途径中的蛋白质降解，并且在细胞内调节中也起关键作用。单克隆抗泛素抗体可用于免疫印迹和酶联免疫吸附测定以定位和检测泛素。小鼠抗泛素抗体在小鼠、人、牛和大鼠中可与泛素发生特异性反应。
Immunogen
与KLH偶联的纯化牛泛素。
Application
单克隆抗泛素抗体可以用于蛋白印迹，以对泛素化的蛋白进行观察和评估。其也可用于微阵列和免疫印迹中。
成功使用该抗体的应用以及相关的同行评审论文如下所示。
蛋白质免疫印迹分析（1篇论文）
蛋白质免疫印迹分析（1篇论文）
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存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Yuga Takahashi et al.
FEBS letters, 585(12), 1741-1747 (2011-05-17)
Nerve growth factor (NGF) binding to its receptor TrkA, which belongs to the family of receptor tyrosine kinases (RTKs), is known to induce its internalization, endosomal trafficking and subsequent lysosomal degradation. The Cbl family of ubiquitin ligases plays a major
Ana P Valencia et al.
BMC musculoskeletal disorders, 18(1), 436-436 (2017-11-11)
Rotator cuff (RTC) tears are a common clinical problem resulting in adverse changes to the muscle, but there is limited information comparing histopathology to contractile function. This study assessed supraspinatus force and susceptibility to injury in the rat model of
Andrej Susor et al.
Reproduction (Cambridge, England), 134(4), 559-568 (2007-09-25)
In this study, we performed proteomic analysis of porcine oocytes during in vitro maturation. Comparison of oocytes at the initial and final stages of meiotic division characterized candidate proteins that were differentially synthesized during in vitro maturation. While the biosynthesis
Kalidou Ndiaye et al.
Journal of ovarian research, 8, 12-12 (2015-04-18)
LAPTM4B is a member of the lysosome-associated transmembrane protein superfamily that is differentially expressed in normal human tissues and upregulated in various types of carcinomas. These proteins are thought to be involved in the regulation of cell proliferation and survival.
Clinton Yu et al.
Nature communications, 6, 10053-10053 (2015-12-04)
The full enzymatic activity of the cullin-RING ubiquitin ligases (CRLs) requires a ubiquitin-like protein (that is, Nedd8) modification. By deamidating Gln40 of Nedd8 to glutamate (Q40E), the bacterial cycle-inhibiting factor (Cif) family is able to inhibit CRL E3 activities, thereby
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