推荐产品
生物来源
mouse
偶联物
unconjugated
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
T311, monoclonal
表单
buffered aqueous solution
分子量
antigen ~70 kDa
种属反应性
human
技术
immunocytochemistry: suitable
immunohistochemistry : suitable
indirect ELISA: suitable
western blot: 1-2 μg/mL using total cell extract of SKMEL19 cells
同位素/亚型
IgG2a
UniProt登记号
运输
dry ice
储存温度
−20°C
基因信息
human ... TYR(7299)
免疫原
recombinant human tyrosinase protein.
外形
Solution in 0.01 M phosphate buffered saline, pH 7.4, and 15 mM sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
常规特殊物品
K S Clarkson et al.
Journal of clinical pathology, 54(3), 196-200 (2001-03-17)
To compare the sensitivity and staining pattern of the new immunohistochemical antibody to tyrosinase (T311) with S-100, HMB45, and the recently evaluated antibody to melan-A (A103) in a range of melanocytic lesions. Archival, formalin fixed, paraffin wax embedded sections from
Tyrosinase exacerbates dopamine toxicity but is not genetically associated with Parkinson's disease.
Elisa Greggio et al.
Journal of neurochemistry, 93(1), 246-256 (2005-03-19)
Tyrosinase is a key enzyme in the synthesis of melanin in skin and hair and has also been proposed to contribute to the formation of neuromelanin (NM). The presence of NM, which is biochemically similar to melanin in peripheral tissues
Y T Chen et al.
Proceedings of the National Academy of Sciences of the United States of America, 92(18), 8125-8129 (1995-08-29)
Tyrosinase (EC 1.14.18.1), the key enzyme in melanin synthesis, has been shown to be one of the targets for cytotoxic T-cell recognition in melanoma patients. To develop serological reagents useful for immunophenotyping melanoma for tyrosinase, human tyrosinase cDNA was expressed
A A Jungbluth et al.
Pathology, research and practice, 196(4), 235-242 (2000-04-27)
Tyrosinase is a key enzyme in melanin biosynthesis and represents a marker of melanocytic differentiation. We previously generated T311, a murine monoclonal antibody to the tyrosinase recombinant protein. This study was performed to evaluate T311 as a diagnostic immunohistochemical reagent
Dake Dong et al.
Lasers in medical science, 29(5), 1649-1654 (2014-04-09)
Both high-intensity ultraviolet and narrowband ultraviolet B (NB-UVB) are important therapeutic options for vitiligo management, but high-intensity ultraviolet is more effective than NB-UVB. However, the underlying mechanisms have not been well investigated. Herein, we compare the effects of high-intensity ultraviolet
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