T9429
抗-转化生长因子-β，pan 兔抗
IgG fraction of antiserum, lyophilized powder
别名:
Anti-TGF-β, pan
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关于此项目
Conjugate:
unconjugated
Clone:
polyclonal
Application:
microarray
neutralization
western blot
neutralization
western blot
Species reactivity:
amphibian, human, pig
Citations:
8
Technique(s):
microarray: suitable
neutralization: suitable
western blot: suitable
neutralization: suitable
western blot: suitable
Uniprot accession no.:
产品名称
抗-转化生长因子-β，pan 兔抗, IgG fraction of antiserum, lyophilized powder
biological source
rabbit
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
amphibian, human, pig
technique(s)
microarray: suitable
neutralization: suitable
western blot: suitable
UniProt accession no.
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... TGFB1(7040), TGFB2(7042), TGFB3(7043)
Biochem/physiol Actions
The antibody will neutralize the biological activity of human TGF-β1, porcine TGF-β1.2, porcine TGF-β2, human TGF-β3, and amphibian TGF-β5.
The effect of intraperitoneal injection of Anti-Transforming Growth Factor-β, pan antibody produced in rabbit in monocrotaline-induced pulmonary hypertension was studied in rat model.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Immunogen
mixture of recombinant human TGF-β1, porcine TGF-β1.2, porcine TGF-β2, and recombinant amphibian TGF-β5.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.
Preparation Note
Purified using protein A.
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存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
此项目有
Ya-Wen Hsiao et al.
Journal of immunology (Baltimore, Md. : 1950), 172(3), 1508-1514 (2004-01-22)
IL-6 is a multifunctional cytokine that regulates cell growth, differentiation, and cell survival. Many tumor cells produce TGF-beta1, which allows them to evade CTL-mediated immune responses. IL-6 antagonizes TGF-beta1 inhibition of CD3 cell activation. However, whether IL-6 restores NK activity
Miao Jia et al.
Frontiers in physiology, 13, 778479-778479 (2022-03-22)
Peritoneal dialysis (PD) is an important part of replacement therapy for kidney failure. However, long-term PD treatment can cause peritoneal fibrosis. Autophagy may be involved in the pathological mechanism of peritoneal fibrosis (PF). Although autophagy is currently known to be
Samuel P Hoile et al.
PloS one, 9(10), e109896-e109896 (2014-10-21)
Studies in animal models and in cultured cells have shown that fatty acids can induce alterations in the DNA methylation of specific genes. There have been no studies of the effects of fatty acid supplementation on the epigenetic regulation of
Steven M Driever et al.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 372(1730) (2017-08-16)
To meet the growing demand for food, substantial improvements in yields are needed. This is particularly the case for wheat, where global yield has stagnated in recent years. Increasing photosynthesis has been identified as a primary target to achieve yield
Aikaterini J Megalou et al.
International journal of clinical and experimental medicine, 3(4), 332-340 (2010-11-13)
The role of transforming growth factor-β in the pathogenesis of pulmonary arterial hypertension is unclear. We examined the effects of T9429, an antibody against transforming growth factor-β receptors, on hemodynamic, histological and functional parameters in the rat model of monocrotaline-induced
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