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Merck
CN

T8951

Sigma-Aldrich

桔皮素

≥95% (HPLC)

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别名:
4′,5,6,7,8-五甲氧基黄酮, 5,6,7,8-四甲基-2-(4-甲氧基苯基)-4H-1-苯并吡喃-4-酮, NSC 53909, NSC 618905, 桔皮素
经验公式(希尔记法):
C20H20O7
CAS号:
分子量:
372.37
Beilstein:
351695
EC 号:
MDL编号:
UNSPSC代码:
12352205
PubChem化学物质编号:
NACRES:
NA.25

质量水平

检测方案

≥95% (HPLC)

应用

metabolomics
vitamins, nutraceuticals, and natural products

SMILES字符串

COc1ccc(cc1)C2=CC(=O)c3c(OC)c(OC)c(OC)c(OC)c3O2

InChI

1S/C20H20O7/c1-22-12-8-6-11(7-9-12)14-10-13(21)15-16(23-2)18(24-3)20(26-5)19(25-4)17(15)27-14/h6-10H,1-5H3

InChI key

ULSUXBXHSYSGDT-UHFFFAOYSA-N

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一般描述

桔皮素是一种多甲氧基黄酮,主要从柑橘类水果的果皮中提取,如 甜橙中国桔子

应用

桔皮素已被用作抗氧化剂和抗真菌剂,用于测试其对 稻瘟病原菌的铁死亡抑制、分生孢子发育和附着胞形成的影响。它还被用作辅助化疗剂,以研究其与5-氟尿嘧啶(5-Fu)联合使用对WiDr结肠癌细胞的细胞毒性作用。

生化/生理作用

体外体内 研究中,桔皮素通过调节几种癌症类型中的不同途径来发挥其抗癌作用。它还具有抗氧化、抗炎和雌激素特性。
桔皮素是一种在柑橘类水果皮中发现的黄酮类化合物,它最有可能对真菌产生天然抗性。 桔皮素已被证明可以抵消肿瘤启动子诱导的细胞间通讯抑制,并可抑制几种癌症细胞的细胞增殖。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

WGK

WGK 3

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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