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质量水平
检测方案
≥95% (HPLC)
应用
metabolomics
vitamins, nutraceuticals, and natural products
SMILES字符串
COc1ccc(cc1)C2=CC(=O)c3c(OC)c(OC)c(OC)c(OC)c3O2
InChI
1S/C20H20O7/c1-22-12-8-6-11(7-9-12)14-10-13(21)15-16(23-2)18(24-3)20(26-5)19(25-4)17(15)27-14/h6-10H,1-5H3
InChI key
ULSUXBXHSYSGDT-UHFFFAOYSA-N
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一般描述
桔皮素是一种多甲氧基黄酮,主要从柑橘类水果的果皮中提取,如 甜橙 和 中国桔子。
应用
桔皮素已被用作抗氧化剂和抗真菌剂,用于测试其对 稻瘟病原菌的铁死亡抑制、分生孢子发育和附着胞形成的影响。它还被用作辅助化疗剂,以研究其与5-氟尿嘧啶(5-Fu)联合使用对WiDr结肠癌细胞的细胞毒性作用。
生化/生理作用
在 体外 和 体内 研究中,桔皮素通过调节几种癌症类型中的不同途径来发挥其抗癌作用。它还具有抗氧化、抗炎和雌激素特性。
桔皮素是一种在柑橘类水果皮中发现的黄酮类化合物,它最有可能对真菌产生天然抗性。 桔皮素已被证明可以抵消肿瘤启动子诱导的细胞间通讯抑制,并可抑制几种癌症细胞的细胞增殖。
警示用语:
Warning
危险声明
危险分类
Acute Tox. 4 Oral
WGK
WGK 3
个人防护装备
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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