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Merck
CN

T7687

Sigma-Aldrich

Anti-Tissue Inhibitor of Metalloproteinase-3, First Loop antibody produced in rabbit

~1 mg/mL, buffered aqueous glycerol solution, affinity isolated antibody

别名:

Anti-TIMP-3

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About This Item

MDL编号:
UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous glycerol solution

种属反应性

human

浓度

~1 mg/mL

技术

western blot: 1:1,000 using a whole cell extract from human fibroblasts (M 3303)

UniProt登记号

运输

wet ice

储存温度

−20°C

基因信息

human ... TIMP3(7078)

特异性

By immunoblotting against the reduced protein, the antibody reacts with bands at ~24 kDa and 30 kDa (unglycosylated and glycosylated, respectively). It also reacts with non-reduced TIMP-3.

免疫原

synthetic peptide corresponding to the first loop of human tissue inhibitor of metalloproteinase-3.

外形

Solution in phosphate buffered saline, pH 7.4, containing 50% glycerol and 0.05% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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象形图

Health hazard

警示用语:

Danger

危险声明

危险分类

Eye Irrit. 2 - Resp. Sens. 1

储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Z Saihan et al.
Molecular vision, 15, 1218-1230 (2009-06-19)
To determine the phenotypic and biochemical characteristics of the p.E139K missense variant in tissue inhibitor of metalloproteinase 3 (TIMP3) associated with Sorsby fundus dystrophy (SFD). The coding regions and adjacent intronic sequence of TIMP3 were amplified by polymerase chain reaction
Sarah Naessens et al.
Human mutation, 40(5), 539-551 (2019-01-23)
Sorsby fundus dystrophy (SFD) is a macular degeneration caused by mutations in TIMP3, the majority of which introduce a novel cysteine. However, the exact molecular mechanisms underlying SFD remain unknown. We aimed to provide novel insights into the functional consequences

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