InChI key
KJUGUADJHNHALS-UHFFFAOYSA-N
InChI
1S/CH2N4/c1-2-4-5-3-1/h1H,(H,2,3,4,5)
SMILES string
c1nnn[nH]1
Quality Level
Application
Not recommended for use in DNA synthesis.
Disclaimer
切勿加热超过 90°C（爆炸危险）
signalword
Danger
hcodes
Hazard Classifications
Self-react. A
存储类别
1 - Explosive hazardous materials
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves
法规信息
新产品
此项目有
Frank H Allen et al.
Journal of chemical information and modeling, 52(3), 857-866 (2012-02-07)
Bioisosterism involving replacement of a carboxylic acid substituent by 1H-tetrazole, yielding deprotonated carboxylate and tetrazolate under physiological conditions, is a well-known synthetic strategy in medicinal chemistry. To improve our overall understanding of bioisosterism, we have used this example to study
Mohamad Sabbah et al.
Bioorganic & medicinal chemistry, 20(15), 4727-4736 (2012-07-04)
New analogues of N-acyl-homoserine-lactone (AHL), in which the amide was replaced by a triazole or tetrazole ring, were prepared and tested for their activity as LuxR-dependent QS modulators. Several compounds showed a level of antagonistic or agonistic activity, notably some
Nieves R Paz et al.
Organic letters, 14(13), 3388-3391 (2012-06-15)
The fragmentation of anomeric alkoxyl radicals (ARF) and the subsequent intramolecular cyclization promoted by hypervalent iodine reagents provide an excellent method for the synthesis of tetrazolo-sugars. This new reaction offers additional advantages for the synthesis of these compounds, including the
Yuko Yoshikawa et al.
Inorganic chemistry, 50(22), 11729-11735 (2011-10-19)
We investigated the effects of antitumor-active tetrazolato-bridged dinuclear platinum(II) complexes [{cis-Pt(NH(3))(2)}(2)(μ-OH)(μ-tetrazolato-N(1),N(2))](2+) (1) and [{cis-Pt(NH(3))(2)}(2)(μ-OH)(μ-tetrazolato-N(2),N(3))](2+) (2) on the higher-order structure of a large DNA molecule (T4 phage DNA, 166 kbp) in aqueous solution through single-molecule observation by fluorescence microscopy. Complexes 1
Zhipeng Yu et al.
Journal of the American Chemical Society, 133(31), 11912-11915 (2011-07-09)
Photoactivatable fluorescent probes are invaluable tools for the study of biological processes with high resolution in space and time. Numerous strategies have been developed in generating photoactivatable fluorescent probes, most of which rely on the photo-"uncaging" and photoisomerization reactions. To
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