T7189
Tumor Necrosis Factor Soluble Receptor II (TNF sRII)/Fc Chimera human
>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture
登录 查看组织和合同定价。
选择尺寸
关于此项目
Form:
lyophilized powder
Assay:
>95% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in NSO cells
Mol wt:
52.6 kDa
产品名称
Tumor Necrosis Factor Soluble Receptor II (TNF sRII)/Fc Chimera human, >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture
biological source
human
recombinant
expressed in NSO cells
assay
>95% (SDS-PAGE)
form
lyophilized powder
potency
0.004-0.016 mg per mL ED50
mol wt
52.6 kDa
packaging
pkg of 50 μg
storage condition
avoid repeated freeze/thaw cycles
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
UniProt accession no.
storage temp.
−20°C
Quality Level
Gene Information
human ... TNFRSF1B(7133)
Analysis Note
The biological activity is measured by its ability to neutralize the TNF-α mediated cytotoxicity in mouse L-929 cells in the presence of the metabolic inhibitor actinomycin D.
Application
Tumor Necrosis Factor Soluble Receptor II (TNF sRII)/Fc Chimera human can be used as a test compound for analyzing the interaction between tumor necrosis factor (TNF) and its two soluble receptors by using surface plasmon resonance (SPR) technique.
Biochem/physiol Actions
Tumor Necrosis Factor Soluble Receptor II (TNF sRII)/Fc Chimera human belongs to TNF family of receptors and mediates the metabolic effects of TNF-α. Tumor Necrosis Factor Soluble Receptor II blocks the TNF-α-induced apoptosis and hence regulates the TNF-α function. It also has a pivotal role in neutralizing the biological activities of both TNF-α and TNF-β.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Matthews, N., et al. et al.
Lymphokines and Interferons, A Practical Approach, 221-221 (1987)
Kinetic Analysis of Interaction Between Tumor Necrosis Factor and Its Soluble Receptors.
<BIG>Fan Yang</BIG>
Journal of Analytical Chemistry, 41 (2013)
Begoña Lainez et al.
International immunology, 16(1), 169-177 (2003-12-23)
Tumor necrosis factor (TNF)-alpha is a pleiotropic cytokine involved in a broad spectrum of inflammatory and immune responses including proliferation, differentiation and cell death induction in several cell types. The biological effects of TNF-alpha are mediated via the cell-surface TNF
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持