T6950
替扎尼定 盐酸盐
≥98% (HPLC), powder
别名:
5-氯-N-（4,5-二氢-1H-咪唑-2-基）-2,1,3-苯并噻二唑-4-胺 盐酸盐
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关于此项目
经验公式（希尔记法）:
C9H9Cl2N5S
化学文摘社编号:
分子量:
290.17
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
产品名称
替扎尼定 盐酸盐, ≥98% (HPLC), powder
InChI
1S/C9H8ClN5S.ClH/c10-5-1-2-6-8(15-16-14-6)7(5)13-9-11-3-4-12-9;/h1-2H,3-4H2,(H2,11,12,13);1H
SMILES string
Cl[H].Clc1ccc2nsnc2c1NC3=NCCN3
InChI key
ZWUKMNZJRDGCTQ-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white
solubility
H2O: >20 mg/mL
originator
Acorda Therapeutics
Quality Level
Gene Information
human ... ADRA2A(150), ADRA2B(151), ADRA2C(152)
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相关类别
Application
盐酸替扎尼定已被用于开发骨骼肌松弛剂验证的分光光度法。
Biochem/physiol Actions
α2-肾上腺素能受体激动剂。
已知盐酸替扎尼定可起到骨骼肌松弛剂中央的作用。此外，这种松弛剂可在脊柱和脊柱上水平起作用，以阻断兴奋性神经元。该药可用于缓解痉挛和疼痛性肌肉痉挛的症状。
Features and Benefits
该化合物由Acorda Therapeutics开发。要浏览其他药物开发化合物和批准的药物/候选药物列表，单击此处。
Preparation Note
盐酸替扎尼定可以高于20 mg/ml的浓度溶于水。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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Mohamed I Walash et al.
Chemistry Central journal, 5, 60-60 (2011-10-11)
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