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安全信息

T6901

Sigma-Aldrich

α1-粘合因子 乙酸盐

≥93% (HPLC), synthetic

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About This Item

经验公式（希尔记法）:
C82H114N20O17S
CAS号:
59401-28-4
分子量:
1683.97
MDL编号:
MFCD00133883
UNSPSC代码:
51111800
PubChem化学物质编号:
24900413
NACRES:
NA.32

生物来源

synthetic

质量水平

200

方案

≥93% (HPLC)

表单

powder

技术

cell culture | mammalian: suitable

储存温度

−20°C

SMILES字符串

CSCCC(NC(=O)C1CCCN1C(=O)C(CCC(N)=O)NC(=O)CNC(=O)C2CCCN2C(=O)C(CCCCN)NC(=O)C(CC(C)C)NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(Cc3c[nH]c4ccccc34)NC(=O)C(Cc5cnc[nH]5)NC(=O)C(N)Cc6c[nH]c7ccccc67)C(=O)NC(Cc8ccc(O)cc8)C(O)=O

InChI

1S/C82H114N20O17S/c1-45(2)34-61(98-76(112)63(38-49-41-89-56-17-9-7-15-53(49)56)99-77(113)64(39-50-42-87-44-91-50)96-71(107)54(84)37-48-40-88-55-16-8-6-14-52(48)55)74(110)93-57(25-27-68(85)104)72(108)97-62(35-46(3)4)75(111)95-59(18-10-11-30-83)80(116)101-31-12-19-66(101)78(114)90-43-70(106)92-60(26-28-69(86)105)81(117)102-32-13-20-67(102)79(115)94-58(29-33-120-5)73(109)100-65(82(118)119)36-47-21-23-51(103)24-22-47/h6-9,14-17,21-24,40-42,44-46,54,57-67,88-89,103H,10-13,18-20,25-39,43,83-84H2,1-5H3,(H2,85,104)(H2,86,105)(H,87,91)(H,90,114)(H,92,106)(H,93,110)(H,94,115)(H,95,111)(H,96,107)(H,97,108)(H,98,112)(H,99,113)(H,100,109)(H,118,119)

InChI key

SBKVPJHMSUXZTA-UHFFFAOYSA-N

Amino Acid Sequence

Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr

应用

α1-交配因子醋酸盐已用于同步酵母细胞流式细胞术并研究经卡尔科弗卢尔荧光增白剂处理的细胞的B型细胞周期蛋白（Clb2p）-EmCitrine 水平。

生化/生理作用

α1-交配因子是一种由酵母产生的用于调节交配的信息素。α1-交配因子醋酸盐可在各种酵母菌株中用于阻滞细胞周期的G1期。

制备说明

Alpha1-交配因子乙酸盐以1mg/ml的浓度溶于水中，得到澄清无色溶液。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

监管及禁止进口产品

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分析证书(COA)

Lot/Batch Number
0000285684
SLCR5753
SLCR5753
0000285684
SLCG3459

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Stefano Vernarecci et al.
Molecular and cellular biology, 28(3), 988-996 (2007-11-28)
We report that the histone acetyltransferase Gcn5p is involved in cell cycle progression, whereas its absence induces several mitotic defects, including inefficient nuclear division, chromosome loss, delayed G(2) progression, and spindle elongation. The fidelity of chromosome segregation is finely regulated
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Eukaryotic cell, 1(5), 811-822 (2002-11-29)
Fungal adhesins represent a large family of serine/threonine-rich secreted glycoproteins. Adhesins have been shown to play roles in heterotypic and homotypic cell-cell adhesion processes, morphogenetic pathways and invasive/pseudohyphal growth, frequently in response to differentiation cues. Here we address the role
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Methods in molecular biology (Clifton, N.J.), 2579, 145-168 (2022-09-01)
The cell division cycle is a fundamental process required for proliferation of all living organisms. The eukaryotic cell cycle follows a basic template with an ordered series of events beginning with G1 (Gap1) phase, followed successively by S (Synthesis) phase
C Formosa et al.
Journal of molecular recognition : JMR, 28(1), 1-9 (2015-06-06)
Single-molecule force spectroscopy using atomic force microscopy (AFM) is more and more used to detect and map receptors, enzymes, adhesins, or any other molecules at the surface of living cells. To be specific, this technique requires antibodies or ligands covalently
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Molecular and cellular biology, 23(18), 6406-6418 (2003-08-29)
Spindle checkpoint proteins monitor the interaction of the spindle apparatus with the kinetochores, halting anaphase even if the microtubule attachment of only a single chromosome is altered. In this study, we show that Bub3p of Saccharomyces cerevisiae, an evolutionarily conserved
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