生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
lyophilized powder
种属反应性
rat
浓度
≥0.6 mg/mL (after reconstitution)
技术
western blot: suitable
UniProt登记号
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
mouse ... Trpc3(22065)
rat ... Trpc3(60395)
一般描述
Transient receptor potential-canonical 3 (TRPC3) is a member of TRP superfamily. It is mainly expressed in brain. The TRPC3 gene is mapped to human chromosome 4.
免疫原
peptide corresponding to amino acid residues 822-835 of mouse TRPC3.
生化/生理作用
TRPC3 (transient receptor potential-canonical 3) participates in motility and capacitation of sperm. It is responsible for the proliferation of ovarian cancer cell in vitro and in vivo. TRPC3 plays a key role in a wide spectrum of Ca2+ signaling mechanisms. Elevated expression of TRPC3 has been observed in spontaneously hypertensive rats (SHR).
外形
Lyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, and 0.05% sodium azide
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
TRPC3: A Multifunctional Signaling Molecule
Lichtenegger M and Groschner K
Handbook of Experimental Pharmacology, 67-84 (2014)
Genotype of an individual single nucleotide polymorphism regulates DNA methylation at the TRPC3 alternative promoter.
Martin-Trujillo A
Epigenetics, 6, 1236-1241 (2011)
Increased Transient Receptor Potential Channel TRPC3 Expression in Spontaneously Hypertensive Rats
Liu D
American Journal of Hypertension, 18, 1503-1507 (2005)
Activation of a TRPC3-Dependent Cation Current through the Neurotrophin BDNF
Li HS
Neuron, 24, 261-273 (1999)
Follicle-stimulating hormone enhances the proliferation of ovarian cancer cells by activating transient receptor potential channel C3
Tao X
Endocrine-Related Cancer, 20, 415-429 (2013)
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