生物来源
goat
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
lyophilized powder
种属反应性
mouse
技术
indirect ELISA: suitable
neutralization: suitable
western blot: suitable
UniProt登记号
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
mouse ... Thpo(21832)
一般描述
This antibody will neutralize the biological activity of recombinant mouse TPO. By ELISA, the antibody shows <15% cross-reactivity with recombinant human TPO.
免疫原
recombinant mouse TPO.
生化/生理作用
Thrombopoietin is a humoral growth factor that is synthesized in the liver and regulates the proliferation and maturation of megakaryocytes, and production of platelets. It modulates the response of platelets to various stimuli by regulating the homeostatic potential.
外形
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 5% trehalose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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法规信息
新产品
Bernhard Wörmann
Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie, 40(5), 319-325 (2013-11-26)
Thrombocytopenia is a common hematologic disorder. Stimulation of thrombopoiesis may reduce the risk for thrombocytopenia-induced bleeding, prevent severe thrombocytopenia, and reduce the need for platelet transfusion. The key cytokine is thrombopoietin (TPO). It regulates proliferation and maturation of megakaryocytes as
Enrico Lupia et al.
Mediators of inflammation, 2012, 390892-390892 (2012-05-12)
Thrombopoietin (TPO) is a humoral growth factor originally identified for its ability to stimulate the proliferation and differentiation of megakaryocytes. In addition to its actions on thrombopoiesis, TPO directly modulates the homeostatic potential of mature platelets by influencing their response
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