T4687
硫柳汞钠
meets USP testing specifications
别名:
Mercury-([o-carboxyphenyl]thio)ethyl 钠盐, 乙基噻吩酸 钠盐, 乙汞硫柳酸钠, 乙汞硫水杨酸 钠盐
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关于此项目
线性分子式:
2-(C2H5HgS)C6H4CO2Na
化学文摘社编号:
分子量:
404.81
EC Number:
200-210-4
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
8169555
MDL number:
InChI key
RTKIYNMVFMVABJ-UHFFFAOYSA-L
InChI
1S/C7H6O2S.C2H5.Hg.Na/c8-7(9)5-3-1-2-4-6(5)10;1-2;;/h1-4,10H,(H,8,9);1H2,2H3;;/q;;2*+1/p-2
SMILES string
[Na+].CC[Hg]Sc1ccccc1C([O-])=O
biological source
synthetic (Organic)
agency
USP/NF, meets USP testing specifications
form
powder
mp
234-237 °C (dec.) (lit.)
cation traces
Hg: ≤0.70% (ions)
mode of action
enzyme | inhibits
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Biochem/physiol Actions
硫柳汞是一种巯基（硫醇）氧化剂，能抑制多种巯基依赖性酶和蛋白质，如PI3激酶依赖性蛋氨酸合成酶、谷氨酸转运受体和Na++K+依赖性ATP酶。
Other Notes
As part of the corporation global plan to support the Minamata Convention eliminating mercury-containing compounds, as of January 2021 customers will be required to provide an End-Use Declaration. Sales of thimerosal will be restricted for approved applications only.
Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place
Disclaimer
For U.S. Customers: Contains mercury; Do not place in trash - dispose according to local, state, or federal laws.
signalword
Danger
Hazard Classifications
Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2 Oral
target_organs
Kidney
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
危险化学品
非剧毒-急性毒性1
此项目有
Anna Kirkland
Social studies of science, 42(2), 237-261 (2012-08-02)
That vaccines do not cause autism is now a widely accepted proposition, though a few dissenters remain. An 8-year court process in the US federal vaccine injury compensation court ended in 2010 with rulings that autism was not an adverse
Alberto Eugenio Tozzi et al.
Developmental medicine and child neurology, 54(9), 843-848 (2012-05-18)
The aim of this article was to explore the effect of duration of breastfeeding on neurocognitive development. The long-term effect of breastfeeding on neurodevelopment was examined through a battery of neuropsychological tests in 1403 children (693 females, 710 males; mean
H Möller
Contact dermatitis, 31(4), 209-213 (1994-10-01)
By and large, positive patch tests with thimerosal lack clinical relevance and should cause concern neither to the dermatologist nor to the patient. The substance should be retained in standard test series for scientific purposes, but on clinical grounds its
J G Elferink
General pharmacology, 33(1), 1-6 (1999-07-31)
An overview of the literature concerning the effects of thimerosal is presented. Because of its antibacterial effect, thimerosal is used for a variety of practical purposes such as antiseptic and preservative. In biomedical studies, thimerosal is used as a sulfhydryl
L Magos
Journal of applied toxicology : JAT, 23(4), 263-269 (2003-07-29)
The decomposition rate of organomercurials and the potency of the blood-brain barrier increase with the size of the organic radical. Thus methylmercury damages the brain more than thimerosal does, and when intake limits set for methylmercury are applied to thimerosal
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