所有图片(2)
About This Item
线性分子式:
4-(HO)C6H4CH2CH(NHCOCH3)CO2H
CAS号:
分子量:
223.23
Beilstein:
2697172
EC 号:
MDL编号:
UNSPSC代码:
12352209
NACRES:
NA.26
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生物来源
non-animal source
方案
≥98.5%
表单
crystalline powder
制造商/商品名称
Ajinomoto
技术
cell culture | mammalian: suitable
杂质
endotoxin, heavy metals, tested
mp
149-152 °C (lit.)
溶解性
H2O: 25 mg/mL
应用
pharmaceutical (small molecule)
SMILES字符串
CC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O
InChI
1S/C11H13NO4/c1-7(13)12-10(11(15)16)6-8-2-4-9(14)5-3-8/h2-5,10,14H,6H2,1H3,(H,12,13)(H,15,16)/t10-/m0/s1
InChI key
CAHKINHBCWCHCF-JTQLQIEISA-N
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一般描述
To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to documentation for this product requires a confidentiality disclosure agreement.
应用
L-Tyrosine is a non-essential amino acid. It can be used as a cell culture media component in the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies. N-Acetyl-L-tyrosine is an acetylated derivative of the essential amino acid L-tyrosine with reported improved nutritional properties.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
J P Eiserich et al.
The Journal of biological chemistry, 271(32), 19199-19208 (1996-08-09)
Detection of 3-nitrotyrosine has served as an in vivo marker for the production of the cytotoxic species peroxynitrite (ONOO-). We show here that reaction of nitrite (NO2-), the autoxidation product of nitric oxide (.NO), with hypochlorous acid (HOCl) forms reactive
Justyna Mrozek et al.
Biophysical chemistry, 111(2), 105-113 (2004-09-24)
The steady-state and time-resolved fluorescence spectroscopy was applied to determine the influence of an alkyl substituent(s) (methyl or ethyl, n-propyl, iso-propyl, n-butyl, sec-butyl, or t-butyl) on amide nitrogen atom on photophysical properties of tyrosine and N-acetyltyrosine amides in water. Generally
Ming-Chou Chiang et al.
The Turkish journal of pediatrics, 50(5), 492-494 (2008-12-24)
Restrictive dermopathy is a rare and lethal autosomal recessive genodermatosis characterized by tight skin, typical dysmorphic face, generalized arthrogryposis and pulmonary hypoplasia. Infants with restrictive dermopathy have similar findings in skin biopsy, but other abnormalities are unremarkable. We report a
M Sharma et al.
Chemico-biological interactions, 108(3), 171-185 (1998-04-07)
Dityrosine (DT) was isolated in a single-step by reversed-phase HPLC in 25% yield from enzyme-catalyzed oxidation of N-acetyl tyrosine followed by deacetylation. The isolated product was characterized by 1H NMR. A three-step chromatographic procedure was reported to facilitate the preparation
M Lehnig
Archives of biochemistry and biophysics, 393(2), 245-254 (2001-09-15)
During reaction of N-acetyl-l-tyrosine with the nitrating system (15)NO(-)(2)/H(2)O(2)/HRP at pH 7.5, emission is observed in the (15)N NMR signals of 3-nitro-N-acetyl-l-tyrosine and the 1-nitrocyclohexa-2,5-dien-4-one derivative of N-acetyl-l-tyrosine. The occurrence of (15)N CIDNP proves the formation of radical pairs. The
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