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T3955

TNP

≥95% (HPLC), IP6K inhibitor, powder

别名:

N2-（间三氟苄基），N6-（对硝基苄基）嘌呤; N6-[（4-硝基苯基）甲基] -N2-[[3-（三氟甲基）苯基]甲基] -9H-嘌呤-2,6-二胺；N6-[（4-硝基苯基）甲基] -N2-[[3-（三氟甲基）苯基]甲基] -1H-嘌呤-2,6-二胺

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关于此项目

经验公式（希尔记法）:
C20H16F3N7O2
化学文摘社编号:
519178-28-0
分子量:
443.38
UNSPSC Code:
12352200
PubChem Substance ID:
329826781
NACRES:
NA.77
MDL number:
MFCD16875436
Assay:
≥95% (HPLC)
Form:
powder
Quality level:
100
Storage condition:
protect from light
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产品名称

TNP, ≥95% (HPLC)

Quality Level

100

assay

≥95% (HPLC)

form

powder

storage condition

protect from light

color

yellow

solubility

DMSO: ≥10 mg/mL

originator

Novartis

storage temp.

2-8°C

SMILES string

[O-][N+](=O)c1ccc(CNc2nc(NCc3cccc(c3)C(F)(F)F)nc4[nH]cnc24)cc1

InChI

1S/C20H16F3N7O2/c21-20(22,23)14-3-1-2-13(8-14)10-25-19-28-17(16-18(29-19)27-11-26-16)24-9-12-4-6-15(7-5-12)30(31)32/h1-8,11H,9-10H2,(H3,24,25,26,27,28,29)

InChI key

DDSBPUYZPWNNGH-UHFFFAOYSA-N

Biochem/physiol Actions

TNP是一种有效的选择性IP6K抑制剂；选择性较低的IP3K抑制剂。 2002年首次报道了TNP作为肌醇三磷酸（IP3）激酶抑制剂的发现，但是，最近的参考资料显示TNP作为IP6K抑制剂更有效，这使其对于肌醇焦磷酸盐的研究具有重要意义。
有效和选择性的IP6K抑制剂；选择性较低的IP3K抑制剂。

Features and Benefits

该化合物由 Novartis 开发。想要浏览其他由制药公司开发的化合物以及已批准药物/候选药物清单，请单击此处。

Preparation Note

TNP可溶于DMSO，溶解浓度大于等于10 mg/ml。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000449309
0000449308
0000449308
0000449309
0000230818

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全球贸易项目编号

货号GTIN
T3955-25MG04061833226803
T3955-5MG04061833226810