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Merck
CN

T3955

TNP

≥95% (HPLC), IP6K inhibitor, powder

别名:

N2-(间三氟苄基),N6-(对硝基苄基)嘌呤; N6-[(4-硝基苯基)甲基] -N2-[[3-(三氟甲基)苯基]甲基] -9H-嘌呤-2,6-二胺;N6-[(4-硝基苯基)甲基] -N2-[[3-(三氟甲基)苯基]甲基] -1H-嘌呤-2,6-二胺

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关于此项目

经验公式(希尔记法):
C20H16F3N7O2
化学文摘社编号:
分子量:
443.38
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥95% (HPLC)
Form:
powder
Quality level:
Storage condition:
protect from light
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产品名称

TNP, ≥95% (HPLC)

SMILES string

[O-][N+](=O)c1ccc(CNc2nc(NCc3cccc(c3)C(F)(F)F)nc4[nH]cnc24)cc1

InChI key

DDSBPUYZPWNNGH-UHFFFAOYSA-N

InChI

1S/C20H16F3N7O2/c21-20(22,23)14-3-1-2-13(8-14)10-25-19-28-17(16-18(29-19)27-11-26-16)24-9-12-4-6-15(7-5-12)30(31)32/h1-8,11H,9-10H2,(H3,24,25,26,27,28,29)

assay

≥95% (HPLC)

form

powder

storage condition

protect from light

color

yellow

solubility

DMSO: ≥10 mg/mL

originator

Novartis

storage temp.

2-8°C

Quality Level

Biochem/physiol Actions

TNP是一种有效的选择性IP6K抑制剂;选择性较低的IP3K抑制剂。 2002年首次报道了TNP作为肌醇三磷酸(IP3)激酶抑制剂的发现,但是,最近的参考资料显示TNP作为IP6K抑制剂更有效,这使其对于肌醇焦磷酸盐的研究具有重要意义。
有效和选择性的IP6K抑制剂;选择性较低的IP3K抑制剂。

Features and Benefits

该化合物由 Novartis 开发。想要浏览其他由制药公司开发的化合物以及已批准药物/候选药物清单,请单击此处

Preparation Note

TNP可溶于DMSO,溶解浓度大于等于10 mg/ml。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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