T3952
Anti-β-Tubulin III Antibody
rabbit polyclonal
别名:
抗-Tuj 1
产品名称
抗-β-微管蛋白III 兔抗, ~1 mg/mL, affinity isolated antibody, buffered aqueous solution
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~50 kDa
species reactivity
human
concentration
~1 mg/mL
technique(s)
western blot: 1:500-1:1,000
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... TUBB3(10381)
mouse ... Tubb3(22152)
rat ... Tubb3(246118)
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General description
微管是异二聚体蛋白，由α- 和β-微管蛋白组成。β-微管蛋白有多种不同的同种型。β-微管蛋白III是神经细胞分化以及静脉和淋巴管瓣的标志物。β-微管蛋白III表达的变化与成神经管细胞瘤有关
抗微管蛋白抗体可用于研究微管蛋白的定位。抗β微管蛋白III抗体具有人β-微管蛋白III特异性。
抗微管蛋白抗体可用于研究微管蛋白的定位。抗β微管蛋白III抗体具有人β-微管蛋白III特异性。
微管蛋白β 3 III类（TUBB3） 位于人类染色体 16q24.3。
Immunogen
对应人 β-微管蛋白 III 残基 151-165 的合成肽。
Application
抗 β-Tubulin III 抗体适用于流式细胞术 (1:200-1:500)、免疫组化 (1:100-1:200)、免疫印迹（约 50 kDa）和 免疫印迹(1:500-1:1,000)。
Biochem/physiol Actions
微管蛋白β3 III 类基因（TUBB3）中的错义突变影响神经元细胞的微管组织，并导致神经系统疾病。TUBB3 突变与导致发育中胎儿畸形的肾小管病变有关。
Physical form
溶剂为含有0.02％叠氮化钠的磷酸盐缓冲盐水。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
常规特殊物品
低风险生物材料
此项目有
Expression of neuron-specific β-III tubulin during olfactory neurogenesis in the embryonic and adult rat.
Roskams, A.,J., et al.
Neuroscience, 83(1), 191-200 (199)
Mutations in the neuronal beta-tubulin subunit TUBB3 result in malformation of cortical development and neuronal migration defects.
Poirier K, et al.
Human Molecular Genetics, 19(22), 4462-4473 (2010)
Seungkoo Lee et al.
European journal of cell biology, 84(2-3), 453-459 (2005-04-12)
Follicular dendritic cells (FDCs) play central roles in the B cell survival, proliferation, and differentiation into memory cells. Here, we show that TuJ1 (class III beta-tubulin) is expressed strongly in FDCs of human lymphoid tissue. TuJ1 has been a marker
Edna Grünblatt et al.
Translational psychiatry, 8(1), 51-51 (2018-03-02)
Methylphenidate (Ritalin) is the most commonly prescribed drug in the treatment of attention-deficit hyperactivity disorder. It is suggested that in vivo, methylphenidate treatment supports cortical maturation, however, the molecular and cellular mechanisms are not well understood. This study aimed to
Valentina Caracciolo et al.
Journal of cellular physiology, 223(2), 519-529 (2010-02-18)
In previous studies, we have shown overexpression and ectopic subcellular distribution of gamma-tubulin and betaIII-tubulin in human glioblastomas and glioblastoma cell lines (Katsetos et al., 2006, J Neuropathol Exp Neurol 65:455-467; Katsetos et al., 2007, Neurochem Res 32:1387-1398). Here we
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