product name
硫代磺素T, used as stain for amyloid
质量水平
形式
powder
组成
Dye content, ≥65%
溶解性
methanol: 1 mg/mL
应用
diagnostic assay manufacturing
hematology
histology
储存温度
room temp
SMILES字符串
[Cl-].CN(C)c1ccc(cc1)-c2sc3cc(C)ccc3[n+]2C
InChI
1S/C17H19N2S.ClH/c1-12-5-10-15-16(11-12)20-17(19(15)4)13-6-8-14(9-7-13)18(2)3;/h5-11H,1-4H3;1H/q+1;/p-1
InChI key
JADVWWSKYZXRGX-UHFFFAOYSA-M
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一般描述
硫黄素T是苯并噻唑类染料,与淀粉样蛋白结合后荧光增强。 硫黄素T已可用于组织学和蛋白质表征。
应用
硫黄素T已被用来鉴别样品中淀粉样纤维的存在。
警示用语:
Danger
危险分类
Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Sens. 1
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Journal of structural biology, 151(3), 229-238 (2005-08-30)
Thioflavin T is a benzothiazole dye that exhibits enhanced fluorescence upon binding to amyloid fibrils and is commonly used to diagnose amyloid fibrils, both ex vivo and in vitro. In aqueous solutions, thioflavin T was found to exist as micelles
Extrinsic fluorescent dyes as tools for protein characterization.
Pharmaceut. Res., 25, 1487-1499 (2008)
Nucleic acids research, 45(2), 541-546 (2016-12-03)
We present a conceptually new reversible nanosensor regulated by a DNA nanoswitch. This system is not only responsive to external stimuli (e.g. ATP) but also can be reversibly switched between 'OFF' and 'ON' states via toehold mediated strand displacement reactions.
Tracking Aggregation and Fibrillation of Globular Proteins Using Terahertz and Far-Infrared Spectroscopies
Taiwan yi Xue Hui za Zhi. Journal of the Formosan Medical Association (2016)
Andrology, 7(5), 603-609 (2019-01-22)
We previously demonstrated the normal mouse epididymal lumen contains a non-pathological amyloid matrix that surrounds spermatozoa and plays important roles in sperm maturation and protection. The objective herein was to present a review of this work, including studies showing the
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