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Merck
CN

T3165

Sigma-Aldrich

7-Methoxy-4-(trifluoromethyl)coumarin

≥99% (TLC)

别名:

Methyl 4-(trifluoromethyl)umbelliferyl ether

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About This Item

经验公式(希尔记法):
C11H7F3O3
CAS号:
分子量:
244.17
Beilstein:
225039
MDL编号:
UNSPSC代码:
12352204
PubChem化学物质编号:
NACRES:
NA.32

检测方案

≥99% (TLC)

形式

powder

溶解性

acetone: 50 mg/mL, clear, colorless to faintly yellow

荧光

λex 333 nm; λem 416 nm in methanol

SMILES字符串

COc1ccc2c(OC(=O)C=C2C(F)(F)F)c1

InChI

1S/C11H7F3O3/c1-16-6-2-3-7-8(11(12,13)14)5-10(15)17-9(7)4-6/h2-5H,1H3

InChI key

HAZHUELNIGDYQH-UHFFFAOYSA-N

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相关类别

应用

7-Methoxy-4-(trifluoromethyl)coumarin has been used as a substrate in cytochrome P450 2E1 (CYP2E1) activity assay and aromatase assay.

生化/生理作用

The enzymatic action of cytochrome P450 2E1 (CYP2E1) on 7-methoxy-4-(trifluoromethyl)coumarin results in a fluorescent product 7-hydroxy-4-(trifluoromethyl)coumarin (HFC) that can be measured at 409/530 nm.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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