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Merck
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主要文件

安全信息

T3034

Sigma-Aldrich

Trehalose 6,6′-dimycolate from Mycobacterium bovis

≥97% 6,6′-mycolate esters basis

别名:

6,6′-Di-O-mycoloyl-α,α-trehalose from Mycobacterium bovis, Cord factor from Mycobacterium bovis

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About This Item

CAS号:
61512-20-7
MDL编号:
MFCD00081533
UNSPSC代码:
12352201
NACRES:
NA.25

生物来源

bacterial (Mycobacterium bovis)

方案

≥97% 6,6′-mycolate esters basis

表单

powder

旋光性

[α]25/D 32 to 35 °, c = 1% (w/v) in chloroform/methanol/water (10:9:1)

储存温度

−20°C

InChI

1S/C130H250O15/c1-5-9-13-17-21-25-29-33-37-41-43-45-47-49-51-53-57-61-65-71-81-89-97-105-117(131)116(104-96-88-80-74-73-78-86-94-102-114-108-112(114)100-92-84-76-68-63-59-55-40-36-32-28-24-20-16-12-8-4)128(140)142-110-120-122(134)124(136)126(138)130(144-120)145-129-125(137)123(135)121(133)119(143-129)109-141-127(139)115(103-95-87-79-70-64-60-56-52-50-48-46-44-42-38-34-30-26-22-18-14-10-6-2)118(132)106-98-90-82-72-66-69-77-85-93-101-113-107-111(113)99-91-83-75-67-62-58-54-39-35-31-27-23-19-15-11-7-3/h111-126,129-138H,5-110H2,1-4H3

InChI key

DJUMKUNMJWRLAX-UHFFFAOYSA-N

生化/生理作用

Cord factor is a glycolipid released from Mycobacterium that becomes toxic and antigenic when it interacts with cell surface lipids. It activates macrophages to release inflammatory cytokines and induces thymic atrophy and granuloma formation in lung and other organs. It is responsible for the necrosis and cavitation observed in secondary tuberculosis.

其他说明

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

监管及禁止进口产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCC8936
BCCC4183
BCBZ9333
BCBW8173
BCBV6644

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Yasunobu Miyake et al.
Journal of immunology (Baltimore, Md. : 1950), 194(11), 5366-5374 (2015-04-19)
C-type lectin receptors expressed in APCs are recently defined pattern recognition receptors that play a crucial role in immune responses against pathogen-associated molecular patterns. Among pathogen-associated molecular patterns, cord factor (trehalose-6,6'-dimycolate [TDM]) is the most potent immunostimulatory component of the

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