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一般描述
TiterMax Gold Adjuvant包含三种必需的组份:一种新的嵌段共聚物,CRL-8300,角鲨烯(一种可代谢的油)和山梨醇单油酸酯。
应用
TiterMax® Gold佐剂已用于:
- 乳化接种动物的可溶性抗原1 (Ag-1),以从XenoMouse平台完全制备人单克隆抗体
- 将 GST-dGIPC(GAIP相互作用蛋白的果蝇同系物)蛋白注射到大鼠体内,产生dGIPC蛋白抗体
- 搭配磷酸盐缓冲盐水(PBS)中的果蝇 CtBP (dCtBP)蛋白,皮下注射到新西兰雌性兔体内
生化/生理作用
TiterMax Gold是一种新型的改进的油包水佐剂。通过开发一种新型嵌段共聚物,并从配方中去除二氧化硅,TiterMax Gold比TiterMax Classic具有更低的毒性和更有效的效果。 乳化剂中TiterMax Gold的最佳体积是TiterMax Classic的两倍。
用等体积的TiterMax® Gold佐剂乳化特定蛋白,对实验动物进行免疫并从中提取抗体。
法律信息
TiterMax is a registered trademark of TiterMax USA, Inc
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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产品编号
说明
价格
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves
Jihyun Kim et al.
Biochemical and biophysical research communications, 402(3), 565-570 (2010-10-30)
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Inhibitory receptors are required for the control of cellular activation and they play essential roles in regulating homeostasis and immunity. We previously identified a human inhibitory C-type lectin-like receptor, MICL (CLEC12A), a heavily glycosylated monomer predominantly expressed on myeloid cells.
Anand Srivastava et al.
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Andrew W Drake et al.
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Two biophysical methods, Biacore and KinExA, were used to kinetically and thermodynamically characterize high-affinity antigen/antibody complexes. Three to five independent experiments were performed on each platform with three different antigen/antibody complexes possessing nanomolar to picomolar equilibrium dissociation constants. By monitoring
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