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质量水平
检测方案
≥93% (HPLC)
形式
powder
杂质
≤8% water (Karl Fischer)
颜色
white to yellow cast
溶解性
water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
储存温度
−20°C
SMILES字符串
CC(=O)N[C@@H](C=O)[C@@H](O)[C@H](O[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](O)[C@H]1NC(C)=O)[C@H](O)CO
InChI
1S/C24H41N3O16/c1-8(32)25-11(4-28)17(36)21(12(35)5-29)42-24-16(27-10(3)34)20(39)22(14(7-31)41-24)43-23-15(26-9(2)33)19(38)18(37)13(6-30)40-23/h4,11-24,29-31,35-39H,5-7H2,1-3H3,(H,25,32)(H,26,33)(H,27,34)/t11-,12+,13+,14+,15+,16+,17+,18+,19+,20+,21+,22+,23-,24-/m0/s1
InChI key
LRDDKCYRFNJZBX-WHFMPQCRSA-N
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应用
N,N′,N′′-Triacetylchitotriose has been used:
- as a competitive inhibitor of the enzymatic activity of lysozyme to treat Macrophages to inhibit the constitutively lysozyme production
- to dock the catalytic cleft of Cel9A (endocellulases)
- as an inhibitory sugar to access the specificity of labelling with gold complexed lectin
生化/生理作用
N,N′,N′′-Triacetylchitotriose is a chitin oligosaccharide, that promotes lysozyme inhibition. Chitin oligosaccharides are associated with many physiological functions. They are biodegradable and are useful in identifying chitin polysaccharides and associated glycoconjugates.
制备说明
Prepared by the method of Barker, S.A., et al., J. Chem. Soc., 2218 (1958).
其他说明
To gain a comprehensive understanding of our extensive range of Oligosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Chitin binding by Thermobifida fusca cellulase catalytic domains
Biotechnology and Bioengineering, 100(4), 644-652 (2008)
Isolation and immunolocalization of a Pinus nigra lectin (PNL) during interaction with the necrotrophs?Heterobasidion annosum and Fusarium avenaceum
Physiological and Molecular Plant Pathology, 59(3), 153-163 (2001)
Lysozyme plays a dual role against the dimorphic fungus Paracoccidioides brasiliensis
Revista Do Instituto De Medicina Tropical De Sao Paulo, 50(3), 169-175 (2008)
Analysis of chitin oligosaccharides by capillary electrophoresis with laser-induced fluorescence
Journal of Chromatography A, 979(1-2), 431-438 (2002)
Carbohydrate research, 339(5), 985-994 (2004-03-11)
Herein we study, through all atom molecular dynamics simulations, the complex between hevein and two N-acetylated chitin oligomers, namely N,N(')-diacetylchitobiose and N,N('),N(")-triacetylchitotriose. The results of the simulations for two disaccharide complexes and one trisaccharide complex show that a carbohydrate oligomer
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