Application
来自鸡蛋白的胰蛋白酶抑制剂已被用于:
- 终止蛋白水解反应
- 在OVO-1溶液中研磨细胞悬浮液以分离视网膜
- 用于皮质解离的磷酸盐缓冲液
Biochem/physiol Actions
卵类粘蛋白具有胰蛋白酶抑制剂活性。它有多个可以与免疫球蛋白E(IgE)结合的构象和线性表位。它稳定性高,可耐受加热和蛋白水解。
General description
卵类粘蛋白或胰蛋白酶抑制剂是大多数禽蛋白中富含的蛋白质。鸡蛋白约由186个氨基酸残基组成,且高度糖基化。三个串联的结构域均与胰蛋白酶抑制剂同源。其免疫原性很高,而且可能是大多数鸡蛋过敏的原因。
Other Notes
一个胰蛋白酶单位将在pH 7.6,25℃,反应体积 3.2 mL,1 cm 光路条件下,每分钟产生0.001 以 BAEE 为底物的 δA 253 。
查看更多关于 胰蛋白酶抑制剂的信息。
signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
动植物来源生物产品
此项目有
Immunopanning purification and long-term culture of human retinal ganglion cells
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Molecular Vision, 16, 2867-2867 (2010)
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Jiang HF, et al.
Journal of virology, 91(12) (2017)
Meeyong Shin et al.
Allergy, asthma & immunology research, 5(1), 42-47 (2013-01-02)
It is known that ovomucoid, an egg allergen, is heat resistant and remains soluble after heating. However, a recent study showed that the antigenic activity of ovomucoid could be reduced by heating when egg white (EW) was mixed with wheat
Manipulation of the N-terminal sequence of the Borna disease virus X protein improves its mitochondrial targeting and neuroprotective potential
Ferree C, et al.
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实验方案
This technical article described the Enzymatic Assay of Trypsin Inhibitor.
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