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Merck
CN

T1892

Sigma-Aldrich

硫黄素S

Practical grade, powder

别名:

Direct Yellow 7

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About This Item

CAS号:
颜色索引号:
49010
EC 号:
MDL编号:
UNSPSC代码:
12171500
NACRES:
NA.47

product name

硫黄素S, practical grade

等级

practical grade

质量水平

形式

powder

颜色

light beige to dark beige, to Dark Brown

溶解性

ethanol: water (1:1): 1 mg/mL

λmax

360-380

应用

diagnostic assay manufacturing
hematology
histology

储存温度

room temp

InChI

1S/C17H19N2S.ClH/c1-12-5-10-15-16(11-12)20-17(19(15)4)13-6-8-14(9-7-13)18(2)3;/h5-11H,1-4H3;1H/q+1;/p-1

InChI key

JADVWWSKYZXRGX-UHFFFAOYSA-M

一般描述

硫黄素S有助于对阿尔茨海默′病中的β-淀粉样斑块进行染色和可视化。硫磺素S可与纤维状β-淀粉样斑块结合, 并且不会在斑块中发生扩散。硫磺素-S染色有助于在整个新皮质、海马和丘脑区域中显现较小的斑块。

应用

硫黄素S已用于对组织切片中的β-淀粉样蛋白结构进行染色和可视化。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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The Journal of Neuroscience, 34(23), 7871-7885 (2014)
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Functional connectivity (FC) studies have gained immense popularity in the evaluation of several neurological disorders, such as Alzheimer's disease (AD). AD is a complex disorder, characterised by several pathological features. The problem with FC studies in patients is that it
Attenuation of beta-amyloid deposition and neurotoxicity by chemogenetic modulation of neural activity
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The Journal of Neuroscience, 36(2), 632-641 (2016)
Exacerbation of cerebral amyloid angiopathy-associated microhemorrhage in amyloid precursor protein transgenic mice by immunotherapy is dependent on antibody recognition of deposited forms of amyloid beta
Racke MM, et al.
The Journal of Neuroscience, 25(3), 629-636 (2005)

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