T1270
硫胺 盐酸盐
BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture
别名:
硫胺素 盐酸盐, 维生素 B 1 盐酸盐
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所有图片(3)
About This Item
经验公式（希尔记法）:
C12H17ClN4OS · HCl
CAS号:
分子量:
337.27
Beilstein:
3851771
EC 号:
MDL编号:
UNSPSC代码:
12352207
eCl@ss:
34058006
PubChem化学物质编号:
NACRES:
NA.75
生物来源
synthetic (organic)
质量水平
产品线
BioReagent
检测方案
≥99.0% (HPLC)
形式
powder
分子量
Mw 337.27 g/mol
技术
cell culture | insect: suitable
cell culture | mammalian: suitable
cell culture | plant: suitable
颜色
white
mp
250 °C (dec.) (lit.)
溶解性
H2O: 50 mg/mL, clear, colorless
应用
agriculture
SMILES字符串
CC1=NC(N)=C(C[N+]2=CSC(CCO)=C2C)C=N1.Cl.[Cl-]
InChI
1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1
InChI key
DPJRMOMPQZCRJU-UHFFFAOYSA-M
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一般描述
硫胺素或维生素B1带正电荷，是所有组织的基本成分。它在骨骼肌、肝脏、肾脏、心脏和大脑中含量较高。硫胺素由一个嘧啶环组成，通过亚甲基桥连接到一个噻唑环。
应用
盐酸硫胺素已被用作以下物质的组分：
- 维生素浓缩原液，用于制备培养火山富盐菌的Hv-Ca培养基
- 三乙酸磷酸盐（TAP）培养基，用于培养雪衣藻
- 改良Bold 3N培养基，用于培养小球藻
生化/生理作用
硫胺素通过硫胺素二磷酸激酶进入细胞膜后转化为二磷酸硫胺素。二磷酸硫胺素是一种活性辅因子，对于许多酶的机制至关重要，这些酶参与柠檬酸循环、糖酵解途径、支链氨基酸降解和磷酸戊糖通路。硫胺素参与将食物转化为能量的过程，供中枢和外周神经系统运作使用。该维生素的低水平与谵妄、Wernicke脑病和Wernicke-Korsakoff综合征有关。盐酸硫胺素是培养细胞能量代谢和氨基酸合成所必需的。它存在于许多经典和无血清配方中。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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