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Merck
CN

T1270

硫胺 盐酸盐

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture

别名:

硫胺素 盐酸盐, 维生素 B 1 盐酸盐

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关于此项目

经验公式（希尔记法）:
C12H17ClN4OS · HCl
化学文摘社编号:
67-03-8
分子量:
337.27
NACRES:
NA.75
PubChem Substance ID:
24899952
eCl@ss:
34058006
UNSPSC Code:
12352207
EC Number:
200-641-8
MDL number:
MFCD00012780
Beilstein/REAXYS Number:
3851771

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产品名称

硫胺 盐酸盐, BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture

mol wt

Mw 337.27 g/mol

InChI key

DPJRMOMPQZCRJU-UHFFFAOYSA-M

InChI

1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1

SMILES string

CC1=NC(N)=C(C[N+]2=CSC(CCO)=C2C)C=N1.Cl.[Cl-]

biological source

synthetic (organic)

product line

BioReagent

assay

≥99.0% (HPLC)

form

powder

technique(s)

cell culture | insect: suitable
cell culture | mammalian: suitable
cell culture | plant: suitable

color

white

mp

250 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL, clear, colorless

application(s)

agriculture

Quality Level

200

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相关类别

Application

盐酸硫胺素已被用作以下物质的组分：
  • 维生素浓缩原液，用于制备培养火山富盐菌的Hv-Ca培养基
  • 三乙酸磷酸盐（TAP）培养基，用于培养雪衣藻
  • 改良Bold 3N培养基，用于培养小球藻

Biochem/physiol Actions

硫胺素通过硫胺素二磷酸激酶进入细胞膜后转化为二磷酸硫胺素。二磷酸硫胺素是一种活性辅因子，对于许多酶的机制至关重要，这些酶参与柠檬酸循环、糖酵解途径、支链氨基酸降解和磷酸戊糖通路。硫胺素参与将食物转化为能量的过程，供中枢和外周神经系统运作使用。该维生素的低水平与谵妄、Wernicke脑病和Wernicke-Korsakoff综合征有关。盐酸硫胺素是培养细胞能量代谢和氨基酸合成所必需的。它存在于许多经典和无血清配方中。

General description

硫胺素或维生素B1带正电荷，是所有组织的基本成分。它在骨骼肌、肝脏、肾脏、心脏和大脑中含量较高。硫胺素由一个嘧啶环组成，通过亚甲基桥连接到一个噻唑环。

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319

Hazard Classifications

Eye Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCN8293
BCCN2484
BCCN0070
BCCL5599
BCCM3832

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