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生物来源
Porcine thyroid
质量水平
表单
powder
分子量
~670 kDa
组成
Iodine, ≥0.3%
氮含量分析
14.0-17.5% total
技术
protein purification: suitable
灰分
≤4%
pI
4.58
UniProt登记号
储存温度
−20°C
基因信息
pig ... TG(100156471)
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生化/生理作用
甲状腺球蛋白已被证明可调节包括碘化钠同向转运蛋白和Pendrin在内的碘转运蛋白的转录。
甲状腺球蛋白是一种参与碘代谢的主要蛋白质。它由一种储存在甲状腺中的含碘蛋白质组成，当甲状腺受到垂体促甲状腺激素(TSH)的刺激时，就会转化为循环中的甲状腺素。甲状腺球蛋白常被用作产生抗体的载体蛋白。它作为载体蛋白的优势来自于其大量的酪氨酸残基，可以通过重氮反应进行偶联。
其他说明
电泳异构。
制备说明
用水 (20 mg/mL) 复溶时，观察到浑浊溶液和一些不溶物。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
监管及禁止进口产品
从最新的版本中选择一种：
分析证书(COA)
Lot/Batch Number
Kotaro Kelley et al.
Nature communications, 13(1), 1857-1857 (2022-04-08)
Cryo-FIB/SEM combined with cryo-ET has emerged from within the field of cryo-EM as the method for obtaining the highest resolution structural information of complex biological samples in-situ in native and non-native environments. However, challenges remain in conventional cryo-FIB/SEM workflows, including
L D Kohn et al.
Trends in endocrinology and metabolism: TEM, 12(1), 10-16 (2001-01-04)
Iodide transport by thyrocytes involves porters on the apical and basal surfaces of the cell facing the follicular lumen and bloodstream, respectively. Recent work identifies pendrin as an apical porter and shows that follicular thyroglobulin is a transcriptional regulator of
Kasinath V Kuravi et al.
The Journal of thoracic and cardiovascular surgery (2021-05-03)
Galactose-α-1,3-galactose (alpha-gal) is a carbohydrate that is ubiquitously expressed in all mammals except for primates and humans. Patients can become sensitized to this antigen and develop alpha-gal syndrome (AGS), or a red meat allergy. Symptoms range from generalized gastroenteritis and
Tanuza Nazmul et al.
Microbiology and immunology, 67(7), 334-344 (2023-05-30)
We first investigated the interactions between several algae-derived lectins and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). We created lectin columns using high-mannose (HM)-type glycan-specific lectins OAA and KAA-1 or core fucose-specific lectin hypninA-2 and conducted binding experiments with SARS-CoV-2. The
Effects of Selenium Supplement on B Lymphocyte Activity in Experimental Autoimmune Thyroiditis Rats.
Yang Li et al.
International journal of endocrinology, 2021, 9439344-9439344 (2021-08-24)
45 healthy and adult female SD rats were randomly divided into three groups: normal control group, EAT model group, and selenium yeast supplement EAT group. The EAT model rats were induced by subcutaneous injection of porcine thyroglobulin and fed with
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