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文件

T111080

DMT-dT亚磷酰胺

Name: DMT-dT亚磷酰胺
Brand: SIGMA

configured for PerkinElmer, configured for Polygen

别名:

5′-O-(4,4′-二甲氧基三苯甲基)-2′-脱氧胸苷-3′-O-[O-(2-氰基乙基)-N,N′-二异丙基亚], 5′-O-[双（4-甲氧基苯基）苯基甲基]-2′-脱氧胸苷, 3′-[2-氰基乙基 N,N-双（1-甲基乙基）亚磷酰胺], DMT-dT酰胺, 胸苷, 5′-O-[双（4-甲氧基苯基）苯基甲基]-, 3′-[2-氰基乙基 N,N-双（1-甲基乙基）亚磷酰胺]

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About This Item

经验公式（希尔记法）:

C₄₀H₄₉N₄O₈P

CAS号:

98796-51-1

分子量:

744.81

MDL编号:

MFCD00055063

UNSPSC代码:

41116107

PubChem化学物质编号:

329826649

NACRES:

NA.51

生物来源

non-animal source (no BSE/TSE risk)

质量水平

200

类型

for DNA synthesis

产品线

Proligo Reagents

检测方案

≥99% (³¹P-NMR)
≥99.0% (reversed phase HPLC)

形式

powder or granules

技术

oligo synthesis: suitable

杂质

≤0.3 wt. % water content (Karl Fischer)

颜色

white to off-white

λ

conforms (UV/VIS Identity)

相容性

configured for PerkinElmer
configured for Polygen

核苷分析

base: deoxythymidine
base protecting group: none
2' protecting group: none
5' protecting group: DMT
deprotection: fast/standard

储存温度

2-8°C

SMILES字符串

COc1ccc(cc1)C(OC[C@H]2O[C@H](C[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)N3C=C(C)C(=O)NC3=O)(c4ccccc4)c5ccc(OC)cc5

InChI

1S/C40H49N4O8P/c1-27(2)44(28(3)4)53(50-23-11-22-41)52-35-24-37(43-25-29(5)38(45)42-39(43)46)51-36(35)26-49-40(30-12-9-8-10-13-30,31-14-18-33(47-6)19-15-31)32-16-20-34(48-7)21-17-32/h8-10,12-21,25,27-28,35-37H,11,23-24,26H2,1-7H3,(H,42,45,46)/t35-,36+,37+,53?/m0/s1

InChI key

UNOTXUFIWPRZJX-CEXSRUIHSA-N

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一般描述

Proligo′s DNA phosphoramidites lead to high-yield and high-quality oligonucleotides due to their high coupling efficiency. The deprotection step of automated oligonucleotide synthesis is integral to synthesis time and final product quality. Exocyclic amine functions are protected by a benzoyl group (dA(bz) and dC(bz)) or isobutyryl group (dG(ib)). Recommended cleavage and deprotection conditions are 8 hours at 55 °C or 24 hours at room temperature using concentrated ammonia solution, for standard base-protected oligonucleotides. DMT-dT Phosphoramidite is configured for Expedite^™ and PolyGen^® Synthesizers.

法律信息

Expedite is a trademark of Applera Corporation or its subsidiaries in the US and/or certain other countries

PolyGen is a registered trademark of PolyGen GmbH.

储存分类代码

13 - Non Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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