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经验公式(希尔记法):
C27H29NaO5S
化学文摘社编号:
分子量:
488.57
EC Number:
263-650-6
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
3861515
MDL number:
InChI key
BAVBEHWEOJMHDS-UHFFFAOYSA-M
InChI
1S/C27H30O5S.Na/c1-15(2)19-13-22(17(5)11-24(19)28)27(21-9-7-8-10-26(21)33(30,31)32-27)23-14-20(16(3)4)25(29)12-18(23)6;/h7-16,28-29H,1-6H3;/q;+1/p-1
SMILES string
[Na+].CC(C)c1cc(c(C)cc1O)C2(OS(=O)(=O)c3ccccc23)c4cc(C(C)C)c([O-])cc4C
assay
≥98%
mp
283-285 °C (dec.) (lit.)
solubility
95% ethanol: 10 mg/mL, clear, dark green
General description
Thymol Blue is a pH indicator with visual transition intervals of pH 1.2 (red) to pH 2.8 (yellow), and pH 8.0 (yellow) to pH 9.2 (blue).
Application
Thymol Blue sodium salt was used to indicate the changes in pH to reflect ionization in multi-component drug formulations.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Ramprakash Govindarajan et al.
Pharmaceutical research, 23(10), 2454-2468 (2006-08-26)
Evaluation of the effect of formulation composition and processing variables on the microenvironment in solid dosage forms, based on ionization of indicator probes. Sulfonephthalein indicators were intimately mixed with individual excipients, binary excipient mixtures or multi-component blends by the solvent
N Gayathri et al.
Journal of AOAC International, 84(4), 1065-1069 (2001-08-15)
A simple and sensitive spectrophotometric method was developed for the determination of trace amounts of sulfur dioxide. The method is based on the reaction of SO2 with a known excess of ICI as the oxidant. The unreacted ICI iodinates thymol
Shangjie Xu et al.
Macromolecular bioscience, 7(8), 968-974 (2007-08-01)
A simple general synthetic concept to build dendritic core-shell architectures with pH-labile linkers based on hyperbranched PEI cores and biocompatible PEG shells is presented. Using these dendritic core-shell architectures as nanocarriers, the encapsulation and transport of polar dyes of different
P Balderas-Hernández et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 66(1), 68-73 (2006-07-11)
This paper presents the results concerning the determination of the formation constants of the complexes between thymol blue, TB, and the metal ions Pb(II) or Cd(II). The experimental procedure was carried out in the presence of a nitrogen atmosphere at
Kanakapura Basavaiah et al.
Anais da Academia Brasileira de Ciencias, 80(2), 253-262 (2008-05-29)
Four sensitive and rapid methods for the determination of stavudine (STV) in bulk drug and in dosage forms were developed and optimized. In titrimetry, aqueous solution of STV was treated with a known excess of bromate-bromide in HCl medium followed
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