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T0656

Sigma-Aldrich

1,3,4,6-四氯-3α,6α-二苯基甘脲

别名:

Iodo-Gen®, NSC 4462

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About This Item

经验公式（希尔记法）:
C16H10Cl4N4O2
CAS号:
51592-06-4
分子量:
432.09
MDL编号:
MFCD00027367
UNSPSC代码:
12352101
PubChem化学物质编号:
24899904
NACRES:
NA.22

储存温度

2-8°C

质量水平

100

SMILES字符串

ClN1C(=O)N(Cl)C2(N(Cl)C(=O)N(Cl)C12c3ccccc3)c4ccccc4

InChI

1S/C16H10Cl4N4O2/c17-21-13(25)23(19)16(12-9-5-2-6-10-12)15(21,11-7-3-1-4-8-11)22(18)14(26)24(16)20/h1-10H

InChI key

FJQZXCPWAGYPSD-UHFFFAOYSA-N

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相关类别

应用

用作氧化剂的放射性碘化用碘化试剂

用于氯胺-T 比较研究的试剂

用于氧化咪唑的试剂

法律信息

Iodo-Gen is a registered trademark of Pierce Biotechnology, Inc.

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H315,H319,H335

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000213687
0000213687
0000203102
0000203102
0000145944

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Helge Wiig et al.
The Journal of physiology, 567(Pt 2), 557-567 (2005-07-05)
Knowledge of macromolecular distribution volumes is essential in understanding fluid transport within normal and pathological tissues. In this study in vivo we determined the distribution volumes of several macromolecules, including one monoclonal antibody, in tumours and tested whether charges associated
E Carnazzi et al.
Journal of medicinal chemistry, 37(12), 1841-1849 (1994-06-10)
A series of new linear photoactivatable and iodinatable antagonists of the neuropeptidic hormone vasopressin was designed and synthesized by a combination of PyBOP-mediated Boc/solid-phase peptide synthesis and solution synthesis approaches. These were based on modifications of a previously reported potent
P K Garg et al.
Bioconjugate chemistry, 6(4), 493-501 (1995-07-01)
The F(ab')2 fragment of monoclonal antibody (MAb) Me1-14 was labeled with 125I using the Iodogen method and by reaction with N-succinimidyl 3-[125I]iodobenzoate (SIB). The labeled catabolites generated after exposure to tissue homogenates in vitro and following administration of labeled F(ab')2
P K Garg et al.
Bioconjugate chemistry, 7(2), 233-239 (1996-03-01)
Two peptides of potential utility for targeting melanoma cells, alpha-melanocyte-stimulating hormone (alpha-MSH) and its more potent analogue [Nle4,D-Phe7]-alpha-MSH, were radioiodinated in 45-65% yield using N-succinimidyl 3-[125I]iodobenzoate (SIB). To determine whether this labeling method resulted in improved in vitro and in
M R Zalutsky et al.
Nuclear medicine and biology, 26(7), 781-790 (2000-01-11)
Monoclonal antibody (MAb) internalization can have a major effect on tumor retention of radiolabel. Two anti-HER-2/neu MAbs (TA1 and 520C9) were radioiodinated using the iodogen, N-succinimidyl 5-iodo-3-pyridinecarboxylate (SIPC), and tyramine-cellobiose (TCB) methods. Paired-label studies compared internalization and cellular processing of
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