应用
10 mM氯化钙用于激活酶。
转谷氨酰胺酶已用于一项可改善可量化分析研究,以充分表征转谷氨酰胺酶在亨廷顿氏病和阿尔茨海默病等疾病中的作用。转谷氨酰胺酶还用于研究转谷氨酰胺酶活性的非放射性斑点印迹试验。
单位定义
一个单元,在pH6.0,37℃下,每分钟将催化Nα-Z-Gln-Gly和羟胺形成1.0 μ摩尔的异羟肟酸酯。(L-谷氨酸γ-单羟肟酸酯为参考标准。)
外形
从50 mM NaH2PO4、150 mM NaCl、pH 8冻干。包含麦芽糖糊精。
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Archives of biochemistry and biophysics, 223(2), 381-392 (1983-06-01)
Valproic acid (dipropylacetic acid), an antiepileptic agent known to be hepatotoxic in some patients, caused inhibition of lactate gluconeogenesis, fatty acid oxidation, and fatty acid synthesis by isolated hepatocytes. The latter process was the most sensitive to valproic acid, 50%
Biochemical pharmacology, 35(2), 289-295 (1986-01-15)
The amino acid conjugation of the phenoxyherbicides 2,4-dichlorophenoxyacetate (2,4-D) and 2,4,5-trichlorophenoxyacetate (2,4,5-T) by animals was examined at the level of the enzymes catalyzing the reactions. The phenoxyherbicides were not substrates for the bile acid conjugating system but were substrates for
Developmental pharmacology and therapeutics, 3(3), 150-159 (1981-01-01)
We report investigations of benzoate and glycine metabolism and glycine acyltransferase activity in rats. These studies provide insights related to the therapy and pathophysiology of human nonketotic hyperglycinemia. Liver acyltransferase activity increased sharply postnatally from low levels at birth, but
Biochemical medicine and metabolic biology, 36(1), 98-105 (1986-08-01)
Prompted by the fact that the urinary excretion of organic acids in the riboflavin-deficient rat closely mimics that found in patients with inborn errors in the acyl-CoA dehydrogenation systems, the organelle localization and the apparent kinetic constants (Km and Vmax
Acyl-CoA esters of xenobiotic carboxylic acids as biochemically active intermediates.
Biochemical Society transactions, 13(5), 856-858 (1985-10-01)
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