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重组
expressed in HEK 293 cells
方案
≥90% (SDS-PAGE)
表单
lyophilized
分子量
~150 kDa by SDS-PAGE
杂质
<0.1 EU/μgtested
UniProt登记号
运输
wet ice
储存温度
−20°C
基因信息
human ... JAG2(3714)
一般描述
Jagged-2 is a putative Notch ligand involved in the mediation of Notch signaling, that can induce stromal cells to secrete IL-6, VEGF and IGF-1. Notch activation can interact with NF-kappaB and C-myc to promote the proliferation and to inhibit the apoptosis of MM cells, showing in the relationship between the incidence of myeloma and drug resistance. Jagged-2 is also involved in limb development.
序列
Human Jagged-2 (aa 1-1054) is fused at the C-terminus to the Fc portion of human IgG.
外形
Lyophilized. Contains PBS + 0.02 % CHAPS.
重悬
Reconstitute with 100μl sterile water.
储存分类代码
12 - Non Combustible Liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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