跳转至内容
Merck
CN
所有图片(1)

主要文件

安全信息

SRP8054

Sigma-Aldrich

Tim-1 (human): FC (human)

recombinant, expressed in CHO cells, ≥98% (SDS-PAGE)

别名:

Hepatitis A virus cellular receptor 1, KIM1, T-cell immunoglobulin and mucin domain-containing protein 1, T-cell immunoglobulin and mucin domain-containing protein 4, TIMD1

登录查看公司和协议定价


About This Item

UNSPSC代码:
12352200
NACRES:
NA.77

生物来源

human

重组

expressed in CHO cells

方案

≥98% (SDS-PAGE)

表单

lyophilized

分子量

monomer 57 kDa by calculation

包装

pkg of 100 μg

储存条件

avoid repeated freeze/thaw cycles

杂质

<0.06 EU/μg endotoxin, tested

颜色

white

UniProt登记号

运输

wet ice

储存温度

−20°C

基因信息

human ... HAVCR1(26762)

一般描述

The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to viral infections. The unique structure of TIM immunoglobulin variable region domains allows highly specific recognition of phosphatidylserine (PtdSer), exposed on the surface of apoptotic cells. TIM-1 (T cell-immunoglobulinmucin; also KIM-1 and HAVcr-1) is a 100 kDa, type I transmembrane glycoprotein member of the TIM family of immunoglobulin superfamily molecules. There are two cytoplasmic alternate splice forms of TIM1. One is a long (359 aa) kidney form termed TIM-1b, and one is a short (334 aa) liver form termed TIM-1a. TIM-1, important for asthma and allergy, is preferentially expressed on T-helper 2 (Th2) cells and functions as a potent costimulatory molecule for T cell activation.

外形

Lyophilized from 0.2 μm-filtered solution in PBS.

重悬

Reconstitute at 100 μg/mL in sterile PBS.

其他说明

The extracellular domain of human Tim-1 (aa 21-295) is fused to the N-terminus of the Fc region of human IgG1.

储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

从最新的版本中选择一种:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本?

如果您需要特殊版本,可通过批号或批次号查找具体证书。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门