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生物来源
mouse
重组
expressed in CHO cells
标签
FLAG® tagged
方案
>95% (SDS-PAGE)
表单
lyophilized
分子量
~47 kDa by SDS-PAGE
包装
pkg of 10 μg
储存条件
avoid repeated freeze/thaw cycles
杂质
<0.01 EU/μg endotoxin, tested
颜色
white
UniProt登记号
运输
wet ice
储存温度
−20°C
基因信息
mouse ... Serpinf1(20317)
一般描述
Pigment epithelium-derived factor (PEDF) is a 47kDa secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and fetal tissues, including brain, spinal cord, plasma, bone, prostate, pancreas, heart and lung. PEDF acts as an angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties. It functions as anti-angiogenic agent by counterbalancing the proangiogenic effect of VEGF. PEDF is one of the most abundant proteins released by adipocytes and induces insulin resistance in adipocytes and human skeletal muscle cells. Recently, it has been reported that PEDF is sufficient to maintain the self-renewal of pluripotent human embryonic stem cells.
外形
Lyophilized from PBS.
重悬
Reconstitute with 100 μL deionized water.
其他说明
Mouse PEDF (aa 20-417) is fused at the C-terminus to a FLAG®-tag.
法律信息
FLAG is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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