推荐产品
生物来源
human
重组
expressed in CHO cells
标签
FLAG® tagged
方案
>95% (SDS-PAGE)
表单
lyophilized
分子量
35-40 kDa by SDS-PAGE
包装
pkg of 10 μg
储存条件
avoid repeated freeze/thaw cycles
杂质
<0.01 EU/μg endotoxin, tested
UniProt登记号
运输
wet ice
储存温度
−20°C
基因信息
human ... CD40LG(959)
一般描述
CD40L (cluster of differentiation 40 ligand) belongs to the tumor necrosis factor (TNF) family, and is expressed by basophils, B cells, monocytic cells, natural killer cells, platelets, mast cells and T cells. It is predominantly expressed on pro-inflammatory T cells. It also exists in a soluble form.
生化/生理作用
CD40L (cluster of differentiation 40 ligand) is active in its membrane-bound form. It interacts with CD40 and functions as a proinflammatory and procoagulant agent. The serum levels of soluble CD40L is elevated in malignant middle cerebral artery infarction (MMCAI) patients, especially in non-surviving patients.
外形
Lyophilized from PBS
重悬
Reconstitute with 100 μL deionized water.
其他说明
Human CD40L (aa 116-261) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG®-tag.
法律信息
FLAG is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex.
Holler N, et al.
Molecular and Cellular Biology, 23(4), 1428-1440 (2003)
Association between Serum Soluble CD154 Levels and Mortality in Patients with Malignant Middle Cerebral Artery Infarction.
Lorente L, et al.
International Journal of Molecular Sciences, 16(6), 12147-12158 (2015)
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