生物来源
mouse
重组
expressed in CHO cells
检测方案
>95% (SDS-PAGE)
形式
liquid
分子量
monomer ~180 kDa by SDS-PAGE (non-reducing)
monomer ~80 kDa by SDS-PAGE (reducing)
包装
pkg of 50 μg
储存条件
avoid repeated freeze/thaw cycles
浓度
≥0.2 mg/mL
杂质
<1 EU/μg endotoxin, tested
颜色
clear
UniProt登记号
运输
wet ice
储存温度
−20°C
基因信息
mouse ... Lag3(16768)
一般描述
Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
外形
Solution in PBS.
其他说明
The sequence coding for the 4 extracellular Ig-like domains of mouse LAG-3 (D1-D4) is fused to the Fc portion of mouse IgG2a (hinge-CH2-CH3).
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
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