生物来源
mouse
重组
expressed in E. coli
偶联物
untagged
检测方案
>95% (SDS-PAGE)
形式
lyophilized
分子量
~17 kDa
包装
pkg of 10 μg
杂质
<0.01 EU/μg endotoxin, tested
颜色
white
UniProt登记号
运输
wet ice
储存温度
−20°C
基因信息
mouse ... Il36g(215257)
相关类别
一般描述
IL-36α (IL-1F6), IL-36β (IL-1F8) and IL-36γ (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1β, IL-6, TNF-α and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.
外形
Lyophilized from PBS and 0.5% trehalose.
重悬
Reconstitute with 100 μL deionized water.
其他说明
IL-36gamma (mouse) (aa 13-164) is untagged.
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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