产品名称
IL-1 Receptor Type I (human): FC (human), recombinant, expressed in HEK 293 cells, >95% (SDS-PAGE)
biological source
human
recombinant
expressed in HEK 293 cells
assay
>95% (SDS-PAGE)
form
lyophilized
mol wt
~80 kDa by SDS-PAGE
packaging
pkg of 50 μg
storage condition
avoid repeated freeze/thaw cycles
impurities
<0.1 EU/μg endotoxin, tested
color
white
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... IL1R1(3554)
General description
IL-1RI is the receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappaB. Signaling involves formation of a ternary complex containing IL1RAP, leading the activation of TOLLIP, MYD88, and IRAK1 or IRAK2.
Other Notes
Human IL-1RI (interleukin-1 receptor type I) (aa 21-336) is fused at the C-terminus to the Fc portion of human IgG1.
Physical form
Lyophilized from PBS.
Preparation Note
Reconstitute with 50 μL deionized water.
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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