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Merck
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安全信息

SRP8028

Sigma-Aldrich

DR6 (human): FC (human)

recombinant, expressed in HEK 293 cells, >95% (SDS-PAGE)

别名:

CD358, TNFRSF21, Tumor necrosis factor receptor superfamily member 21

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About This Item

UNSPSC代码:
12352202
NACRES:
NA.32

生物来源

human

重组

expressed in HEK 293 cells

检测方案

>95% (SDS-PAGE)

形式

lyophilized

分子量

~80 kDa by SDS-PAGE

包装

pkg of 50 μg

储存条件

avoid repeated freeze/thaw cycles

杂质

<0.1 EU/μg endotoxin, tested

颜色

white

UniProt登记号

运输

wet ice

储存温度

−20°C

基因信息

一般描述

DR6 is an orphan TNF receptor superfamily member belonging to a subgroup of receptors called death receptors. Expressed ubiquitously with high expression in lymphoid organs, heart, brain, and pancreas. Broadly expressed by developing neurons where it functions as pro-apoptotic factor. Recently, it has been reported that interaction with the beta-amyloid precursor protein (APP) activates a widespread caspase-dependent self-destruction program dependent on caspase-6.

外形

Lyophilized from PBS.

重悬

Reconstitute with 50 μL deionized water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein.

其他说明

The Fc portion of human IgG1 is fused to the C-terminus of human DR6 (aa 42-351).

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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