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Merck
CN
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安全信息

SRP6553

Sigma-Aldrich

CIRBP/冷诱导 RNA 结合蛋白 人

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

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别名:
A18HNRNP, CIRP
UNSPSC代码:
12352200
NACRES:
NA.32

生物来源

human

重组

expressed in E. coli

检测方案

≥90% (SDS-PAGE)

形式

lyophilized

分子量

20.5 kDa

包装

pkg of 1 mg
pkg of 20 μg

杂质

≤1 EU/μg endotoxin (LAL test)

UniProt登记号

运输

wet ice

储存温度

−70°C

基因信息

human ... CIRBP(1153)

一般描述

CIRBP, also known as cold-inducible RNA-binding protein, plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP responds to a wide array of cellular stresses, including short wavelength ultraviolet light (UVC), at the transcriptional and post-translational level. It acts as a translational activator. CIRBP can bind the 3′untranslated region of specific transcripts to stabilize them and facilitate their transport to ribosomes for translation. CIRBP affects NF-κB signaling as opposed to IL1B mRNA stability directly.

外形

Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 0.25 M Imidazole, 20% glycerol.

重悬

Detailed reconstitution instructions are sent along with the product

象形图

Health hazardExclamation mark

警示用语:

Danger

危险声明

危险分类

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

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