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生物来源
human
重组
expressed in E. coli
方案
≥85% (SDS-PAGE)
表单
liquid
分子量
33.8 kDa (302 aa, 35-313 aa + His tag)
包装
pkg of 100 μg
浓度
1 mg/mL
杂质
<1 EU/μg endotoxin (LAL test)
UniProt登记号
运输
dry ice
储存温度
−70°C
基因信息
human ... CD46(4179)
一般描述
Membrane cofactor protein isoform 14, also known as CD46, is a type I membrane protein that has cofactor activity for inactivation of complement components C3b and C4b by serum factor I. This function resides in the complement control protein repeats (CCPs), with CCP1-4 essential for regulation. CD46 is widely distributed on thymocytes, T cells, B cells, monocytes, granulocytes, NK cells, platelets, endothelial cells, epithelial cells, fibroblasts, placenta and sperm, but not on erythrocyte. Recombinant human CD46 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
外形
1 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl and 20% glycerol.
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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