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生物来源
human
重组
expressed in E. coli
方案
≥90% (SDS-PAGE)
表单
liquid
分子量
24.8 kDa (225 aa, 31-232 aa + His tag)
包装
pkg of 50 μg
浓度
1 mg/mL
杂质
<1 EU/μg endotoxin (LAL test)
UniProt登记号
运输
dry ice
储存温度
−70°C
基因信息
human ... CD200(4345)
一般描述
CD200 is a type-1 membrane glycoprotein, which contains two immunoglobulin domains, and thus belongs to the immunoglobulin superfamily. Studies of the related genes in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene. Recombinant human CD200 protein, fused to His-tag at N-terminus, was expressed in E.coli.
外形
1 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea.
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
历史批次信息供参考:
Stanislava Pankratova et al.
Molecular neurobiology, 53(1), 584-594 (2014-12-17)
The CD200 ligand is expressed by a variety of cell types, including vascular endothelia, kidney glomeruli, some subsets of T and B cells, and neurons in the brain and periphery. In contrast, the receptor of CD200, CD200R, has a limited
Li-Chun Weng et al.
Journal of reproductive immunology, 138, 103090-103090 (2020-02-06)
Endometriosis (EMS) is a benign disease that is related to estrogen, immune disorders and inflammation. The purpose of this research was to determine the expression of CD200 in EMS and to clarify its role in the pathogenesis of the disease.
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