推荐产品
生物来源
human
方案
≥95% (SDS-PAGE)
表单
frozen liquid
分子量
29 kDa
包装
pkg of 25 μg
UniProt登记号
运输
dry ice
储存温度
−70°C
基因信息
human ... AGP7(5657)
一般描述
Proteinase 3 is one of the serine proteinases localized in azurophil granules of polymorphonuclear leukocytes. It has been identified as the autoantigen of Wegener granulomatosis, a systemic vasculitis complicated by melomonocyte proliferation. It exhibits proteolytic activity towards a range of substrates. It is physiologically inhibited by α1-antitrypsin. The protein has been described as having antibiotic and growth-promoting properties and causing emphysema when administered by tracheal insufflation. Proteinase 3 (PR-3) is also known as myeloblastin and p29b.
外形
Frozen in 50 mM MES, pH 4.5 with 700 mM NaCl.
储存分类代码
11 - Combustible Solids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
高风险级别生物产品--人源产品
从最新的版本中选择一种：
分析证书(COA)
Lot/Batch Number
Jeppe Thorlacius-Ussing et al.
Journal of cancer research and clinical oncology, 145(2), 383-392 (2018-11-24)
Elastin is a signature protein of lungs. Increased elastin turnover driven by altered proteolytic activity is an important part of lung tumorigenesis. Elastin-derived fragments have been shown to be pro-tumorigenic, however, little is known regarding the biomarker potential of such
Luis M Molinos-Albert et al.
Nature communications, 13(1), 1944-1944 (2022-04-13)
HIV-1 post-treatment controllers are rare individuals controlling HIV-1 infection for years after antiretroviral therapy interruption. Identification of immune correlates of control in post-treatment controllers could aid in designing effective HIV-1 vaccine and remission strategies. Here, we perform comprehensive immunoprofiling of
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