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一般描述
Native, human eosinophil peroxidase is a secreted hemoprotein that catalyzes oxidations of various substrates by hydrogen peroxide. Together with other leukocyte-derived enzymes, such as Myeloperoxidase, EPO plays an important role in the pathogenesis of asthma by mediating oxidative events that lead to the production of ROS (reactive oxygen species) and RNS (reactive nitrogen species).
外形
Lyophilized from 20 mM NaH2PO4, pH 7.5, and 150 mM NaCI.
重悬
Reconstitute in deionized H₂O. Aliquot and store at –20°C. Avoid freeze-thaw cycles.
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Jorge Sánchez et al.
Allergy, asthma & immunology research, 13(5), 746-761 (2021-09-07)
Eosinophils are frequently found in atopic dermatitis (AD) and chronic spontaneous urticaria (CSU) that release eosinophil peroxidase (EPX) and eosinophil cationic protein (ECP). Continuous exposure to these proteins could trigger an autoimmune response which may contribute to the pathogenesis and
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