推荐产品
生物来源
human
重组
expressed in HEK 293 cells
方案
≥95% (SDS-PAGE)
表单
lyophilized
效能
0.02-0.08 ng/mL
分子量
21-25 kDa (monomer, glycosylated)
包装
pkg of 10 μg
储存条件
avoid repeated freeze/thaw cycles
技术
cell culture | mammalian: suitable
NCBI登记号
UniProt登记号
运输
dry ice
储存温度
−20°C
基因信息
human ... CSF3(1440)
一般描述
Granulocyte colony stimulating factor (G-CSF) or colony stimulating factor 3 (CSF-3) is a cytokine. The active protein is found extracellularly. Three transcript variants encoding three different isoforms have been found for the GCSF gene. Human and murine G-CSF is cross-species reactive. The gene encoding G-CSF is localized on human chromosome 17.
生化/生理作用
Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation and function of two related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Granulocyte colony stimulating factor (G-CSF) controls the production, differentiation and function of granulocytes. It has been shown to have a role in bone repair in animal models. G-CSF has been clinically approved for neutropenia treatment.
外形
Lyophilized from a PBS solution.
制备说明
Centrifuge the vial prior to opening.
重悬
Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
从最新的版本中选择一种：
分析证书(COA)
Lot/Batch Number
Lian Cai et al.
PloS one, 15(3), e0230247-e0230247 (2020-03-18)
Granulocyte-colony stimulating factor (G-CSF), a pleiotropic cytokine, belongs to the hematopoietic growth factor family. Recent studies have reported that G-CSF is a predictive biomarker of oocyte and embryo developmental competence in humans. The aim of our study was to determine
Frequent loss of heterozygosity on chromosome 17 at 17q11.2-q12 in Barrett's adenocarcinoma.
Swift A
British Journal of Cancer, 71(5), 995-998 (1995)
Effect of Granulocyte-Colony Stimulating Factor on Endothelial Cells and Osteoblasts.
Liu XL
BioMed Research International, 8485721-8485721 (2016)
Administration of granulocyte colony-stimulating factor with radiotherapy promotes tumor growth by stimulating vascularization in tumor-bearing mice.
Kim JS
Oncology Reports, 34(1), 147-154 (2015)
Protective role of G-CSF in dextran sulfate sodium-induced acute colitis through generating gut-homing macrophages.
Meshkibaf S
Cytokine, 78, 69-78 (2016)
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