生物来源
human
重组
expressed in human cells
检测方案
≥95% (SDS-PAGE)
形式
lyophilized
分子量
(17 and 30 kDa, monomer, glycosylated)
包装
pkg of 10 μg
技术
cell culture | mammalian: suitable
NCBI登记号
UniProt登记号
运输
dry ice
储存温度
−70°C
基因信息
human ... FGF7(2252)
一般描述
Fibroblast growth factor-7 (FGF-7) is a member of the fibroblast growth factor family. FGF family members possess broad mitogenic and cell survival activities. The gene encoding this protein is localized on human chromosome 15q21.1.
生化/生理作用
Fibroblast growth factor (FGF) family members are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. This protein associates with and activates fibroblast growth factor receptors (FGFRs). Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, re-epithelialization of wounds, hair development and early lung organogenesis.
外形
Lyophilized from a PBS solution.
制备说明
Centrifuge the vial prior to opening.
重悬
Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
The Fibroblast Growth Factor signaling pathway.
Ornitz DM and Itoh N
Wiley Interdisciplinary Reviews. Systems Biology and Medicine, 4(3), 215-266 (2015)
A family-based association study after genome-wide linkage analysis identified two genetic loci for renal function in a Mongolian population.
Park H
Kidney International, 83(2), 285-292 (2013)
Laxmi Yeruva et al.
mBio, 5(3), e01241-e01214 (2014-06-26)
It is not currently possible to predict the probability of whether a woman with a chlamydial genital infection will develop pelvic inflammatory disease (PID). To determine if specific biomarkers may be associated with distinct chlamydial pathotypes, we utilized two Chlamydia
Challenges in Establishing Pure Lung Cancer Organoids Limit Their Utility for Personalized Medicine.
Krijn K Dijkstra et al.
Cell reports, 31(5), 107588-107588 (2020-05-07)
Clinical implementation of tumor organoids for personalized medicine requires that pure tumor organoids can be reliably established. Here, we present our experience with organoid cultures from >70 non-small cell lung cancer (NSCLC) samples. We systematically evaluate several methods to identify
Xiao-Jing Zhu et al.
PLoS genetics, 10(10), e1004687-e1004687 (2014-10-21)
Epidermal stratification of the mammalian skin requires proliferative basal progenitors to generate intermediate cells that separate from the basal layer and are replaced by post-mitotic cells. Although Wnt signaling has been implicated in this developmental process, the mechanism underlying Wnt-mediated
商品
Role of growth factors in stem cell differentiation and various growth factors for your research at sigmaaldrich.com
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门