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生物来源
human
重组
expressed in E. coli
方案
≥90% (SDS-PAGE)
表单
liquid
分子量
40.4 kDa (377 aa, 1-357 aa + NT His Tag)
包装
pkg of 100 μg
储存条件
avoid repeated freeze/thaw cycles
NCBI登记号
运输
dry ice
储存温度
−70°C
基因信息
human ... SORD(6652)
一般描述
SORD, also known as L-iditol 2-dehydrogenase or SORD1, is a 357 amino acid member of the zinc containing alcohol dehydrogenase family. It is widely expressed with highest expression in kidney and in the lens of the eye. SORD enzymatically catalyzes the zinc-dependent interconversion of polyols, such as sorbitol and xylitol, to their respective ketoses.
外形
0.5 mg/mL solution in 20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 5 mM DTT and 20% glycerol.
制备说明
Centrifuge the vial prior to opening.
其他说明
MGSSHHHHHH SSGLVPRGSH MAAAAKPNNL SLVVHGPGDL RLENYPIPEP GPNEVLLRMH SVGICGSDVH YWEYGRIGNF IVKKPMVLGH EASGTVEKVG SSVKHLKPGD RVAIEPGAPR ENDEFCKMGR YNLSPSIFFC ATPPDDGNLC RFYKHNAAFC YKLPDNVTFE EGALIEPLSV GIHACRRGGV TLGHKVLVCG AGPIGMVTLL VAKAMGAAQV VVTDLSATRL SKAKEIGADL VLQISKESPQ EIARKVEGQL GCKPEVTIEC TGAEASIQAG IYATRSGGTL VLVGLGSEMT TVPLLHAAIR EVDIKGVFRY CNTWPVAISM LASKSVNVKP LVTHRFPLEK ALEAFETFKK GLGLKIMLKC DPSDQNP
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Miguel A Lanaspa et al.
Nature communications, 4, 2434-2434 (2013-09-12)
Carbohydrates with high glycaemic index are proposed to promote the development of obesity, insulin resistance and fatty liver, but the mechanism by which this occurs remains unknown. High serum glucose concentrations are known to induce the polyol pathway and increase
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