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Merck
CN
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主要文件

安全信息

SRP6122

Sigma-Aldrich

AK2 human

recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

别名:

ADK2, ATP-AMP phophotransferase, ATP-AMP transphosphorylase 2, Adenylate kinase 2, Adenylate monophosphate kinase

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About This Item

UNSPSC代码:
12352200
NACRES:
NA.32

生物来源

human

重组

expressed in E. coli

方案

≥95% (SDS-PAGE)

表单

liquid

分子量

28.6 kDa (259 aa, 1-239 aa + NT His Tag)

包装

pkg of 100 μg

NCBI登记号

运输

dry ice

储存温度

−70°C

基因信息

human ... AK2(204)

一般描述

Adenylate kinase (AK; adenosine triphosphate-adenosine monophosphate [ATP-AMP] phosphotransferase) is a ubiquitous monomeric enzyme involved energy metabolism of prokaryotic and eukaryotic cells. Three isozymes (AK1, AK2 and AK3) are characterized in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. AK2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis.

外形

1 mg/mL solution in 20 mM Tris-HCl buffer (pH 7.5) containing 5 mM DTT and 20% glycerol.

制备说明

Centrifuge the vial prior to opening.

其他说明

MGSSHHHHHH SSGLVPRGSH MAPSVPAAEP EYPKGIRAVL LGPPGAGKGT QAPRLAENFC VCHLATGDML RAMVASGSEL GKKLKATMDA GKLVSDEMVV ELIEKNLETP LCKNGFLLDG FPRTVRQAEM LDDLMEKRKE KLDSVIEFSI PDSLLIRRIT GRLIHPKSGR SYHEEFNPPK EPMKDDITGE PLIRRSDDNE KALKIRLQAY HTQTTPLIEY YRKRGIHSAI DASQTPDVVF ASILAAFSKA TCKDLVMFI

象形图

Corrosion

警示用语:

Danger

危险声明

预防措施声明

危险分类

Eye Dam. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Ru-Ping Chen et al.
BMC molecular biology, 13, 31-31 (2012-10-02)
Adenylate kinase 2 (AK2) is a phosphotransferase that catalyzes the reversible reaction 2ADP(GDP) ↔ ATP(GTP) + AMP and influences cellular energy homeostasis. However, the role of AK2 in regulating cell proliferation remains unclear because AK2 has been reported to be involved in

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