重组
expressed in baculovirus infected Sf9 cells
检测方案
≥70% (SDS-PAGE)
形式
buffered aqueous glycerol solution
分子量
~62 kDa
NCBI登记号
运输
dry ice
储存温度
−70°C
基因信息
human ... ING2(3622)
一般描述
p33ING2 is a member of the inhibitor of growth (ING) family that is associate with and modulates the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis. P33ING2 is a DNA damage-inducible gene that negatively regulates cell proliferation through activation of p53 by enhancing its acetylation. P33ING2 is required for initial DNA damage sensing and chromatin remodeling in the nucleotide excision repair process.
外形
Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
制备说明
After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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