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Merck
CN

SRP5029

Sigma-Aldrich

FAK, active, GST tagged human

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

别名:

FADK, FAK1, FRNK, PTK2, pp125FAK

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About This Item

UNSPSC代码:
12352200
NACRES:
NA.32

重组

expressed in baculovirus infected Sf9 cells

产品线

PRECISIO® Kinase

方案

≥70% (SDS-PAGE)

表单

buffered aqueous glycerol solution

比活

24-32 nmol/min·mg

分子量

~140 kDa

NCBI登记号

运输

dry ice

储存温度

−70°C

基因信息

human ... PTK2(5747)

外形

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

制备说明

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

法律信息

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

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分析证书(COA)

Lot/Batch Number

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访问文档库

Phosphatidylinositol 4,5-bisphosphate triggers activation of focal adhesion kinase by inducing clustering and conformational changes.
Gorii GM
Proceedings of the National Academy of Sciences of the USA (2014)
FAK signaling in anaplastic astrocytoma and glioblastoma tumors.
Natarajan M
Cancer (2003)
The focal adhesion kinase--a regulator of cell migration and invasion.
Hauck CR
IUBMB Life (2002)
Gain of miR-151 on chromosome 8q24.3 facilitates
tumour cell migration and spreading through
downregulating RhoGDIA
Nature Cell Biology (2010)
Focal adhesion kinase is involved in rabies virus infection through its interaction with viral phosphoprotein P.
Fouquet B
Journal of Virology (2015)

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