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Merck
CN

SRP5029

FAK, active, GST tagged human

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

别名:

FADK, FAK1, FRNK, PTK2, pp125FAK

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关于此项目

NACRES:
NA.32
UNSPSC Code:
12352200
Form:
buffered aqueous glycerol solution
Assay:
≥70% (SDS-PAGE)
Recombinant:
expressed in baculovirus infected Sf9 cells
Mol wt:
~140 kDa
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recombinant

expressed in baculovirus infected Sf9 cells

product line

PRECISIO® Kinase

assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

specific activity

24-32 nmol/min·mg

mol wt

~140 kDa

NCBI accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... PTK2(5747)

Physical form

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Preparation Note

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Amplification of F-Actin Disassembly and Cellular Repulsion by Growth Factor Signaling
Jimok Yoon
Developmental Cell (2017)
Focal adhesion kinase is involved in rabies virus infection through its interaction with viral phosphoprotein P.
Fouquet B
Journal of Virology (2015)
FAK signaling in anaplastic astrocytoma and glioblastoma tumors.
Natarajan M
Cancer (2003)
Phosphatidylinositol 4,5-bisphosphate triggers activation of focal adhesion kinase by inducing clustering and conformational changes.
Gorii GM
Proceedings of the National Academy of Sciences of the USA (2014)
The focal adhesion kinase--a regulator of cell migration and invasion.
Hauck CR
IUBMB Life (2002)

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