推荐产品
生物来源
rat
重组
expressed in E. coli
方案
≥90% (SDS-PAGE)
表单
lyophilized
分子量
~30 kDa
包装
pkg of 25 μg
杂质
endotoxin, tested
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
基因信息
rat ... Adipoq(246253)
一般描述
Adiponectin (also called Acrp30, AdipoQ) is an adipocyte specific secreted protein that circulates in the plasma. It is induced during adipocyte differentiation and the secretion is stimulated by insulin.
生化/生理作用
Adiponectin plays a role in various physiological processes such as energy homeostasis and obesity. Plasma levels of adiponectin are reduced in obese humans, and decreased levels are associated with insulin resistance and hyperinsulinemia. Adiponectin regulates vascular function, sustains an anti-inflammatory environment and promotes angiogenesis.
外形
Lyophilized from a 0.2 μm filtered solution in 25 mM Tris, 0.15 M NaCl, pH 7.4 containing 50 μg of bovine serum albumin (BSA) per 1 μg of adiponectin.
重悬
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Recontitute in PBS containing at least 0.1% BSA to a concentration of 0.1-1.0 mg/mL. This stock solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Elevated adiponectin expression promotes adipose tissue vascularity under conditions of diet-induced obesity.
Aprahamian TR
Metabolism and Disease, 62(12), 1730-1738 (2013)
Deficiency of adiponectin protects against ovariectomy-induced osteoporosis in mice.
Wang F
PLoS ONE, 8(7), e68497-e68497 (2013)
Sergio García-Méndez et al.
Medicine, 94(26), e935-e935 (2015-07-02)
The aim of this study was to determine the levels of leptin (Lep) and adiponectin (AdipoQ) in patients with gout and its relationship with joint inflammatory data and/or with metabolic syndrome (MetS) variables, during 1 year follow-up.Forty-one patients (40 males)
Marcia J Abbott et al.
PloS one, 10(7), e0134290-e0134290 (2015-08-01)
Epidemiological studies show that high circulating levels of adiponectin are associated with low bone mineral density. The effect of adiponectin on skeletal homeostasis, on osteoblasts in particular, remains controversial. We investigated this issue using mice with adipocyte-specific over-expression of adiponectin
商品
Lipid Induced Insulin Resistance
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