生物来源
human
重组
expressed in E. coli
检测方案
≥95% (HPLC)
≥95% (SDS-PAGE)
形式
lyophilized
分子量
~22.3 kDa
包装
pkg of 20 μg
储存条件
avoid repeated freeze/thaw cycles
技术
cell based assay: suitable
杂质
endotoxin, tested
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
基因信息
human ... CSH1(1442)
一般描述
Human placental lactogen (HPL), also called human chorionic somatomammotropin 1, is a polypeptide placental hormone. Its structure and function is similar to that of growth hormone. The gene encoding this protein is localized on human chromosome 17. Recombinant human placental lactogen is a 22.3kDa protein.
生化/生理作用
Human placental lactogen (HPL) modifies the metabolic state of the mother during pregnancy to facilitate the energy supply, glucose supply and growth of the fetus. Studies show that targeted expression of this protein in transgenic mice lead to an increase in proliferation of β-cells.
外形
Sterile filtered and lyophilized with no additives.
重悬
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in water to a concentration of 0.1-1.0 mg/mL. This solution can then be diluted into other aqueous buffers.
法规信息
新产品
Ginkgolic acid and anacardic acid are specific covalent inhibitors of SARS-CoV-2 cysteine proteases.
Zinuo Chen et al.
Cell & bioscience, 11(1), 45-45 (2021-03-01)
In the urgent campaign to develop therapeutics against SARS-CoV-2, natural products have been an important source of new lead compounds. We herein identified two natural products, ginkgolic acid and anacardic acid, as inhibitors using a high-throughput screen targeting the SARS-CoV-2
A study of association between common variation in the growth hormone-chorionic somatomammotropin hormone gene cluster and adult fasting insulin in a UK Caucasian population.
Freathy RM
Journal of Negative Results in Biomedicine, 5, 18-18 (2006)
Meltem Muftuoglu et al.
Nucleic acids research, 34(1), 295-304 (2006-01-18)
Cockayne syndrome (CS) is a rare inherited human genetic disorder characterized by UV sensitivity, severe neurological abnormalities and prageroid symptoms. The CS complementation group B (CSB) protein is involved in UV-induced transcription coupled repair (TCR), base excision repair and general
Placental lactogen is expressed but is not translated into protein in breast cancer.
Tuttle TR
PLoS ONE, 9(1), e87325-e87325 (2014)
Marco F Lombardo et al.
Islets, 3(5), 250-258 (2011-07-19)
The search for factors either promoting islets proliferation or survival during adult life is a major issue for both type 1 and 2 diabetes mellitus. Among factors with mitogenic activity on pancreatic β-cells, human placental lactogen (hPL) showed stronger activity
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门