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安全信息

SRP4757

Sigma-Aldrich

GDF-3 human

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)

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别名:
Growth Diffrentiation Factor-3, Growth/Differentiation Factor-3
MDL编号:
UNSPSC代码:
12352202
NACRES:
NA.32

生物来源

human

重组

expressed in E. coli

检测方案

≥98% (HPLC)
≥98% (SDS-PAGE)

形式

lyophilized

分子量

~13 kDa

包装

pkg of 20 μg

储存条件

avoid repeated freeze/thaw cycles

杂质

endotoxin, tested

NCBI登记号

UniProt登记号

运输

wet ice

储存温度

−20°C

基因信息

human ... GDF3(9573)

一般描述

GDF-3 is a member of the TGF-β superfamily of growth and differentiation factors, and is highly homologous to GDF-9. Unlike most TGF-β family members, GDF-3 and GDF-9 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia which characterizes Type-2 diabetes. Recombinant human GDF-3 contains 114 amino acids polypeptide chains

外形

Sterile filtered and lyophilized with no additives.

重悬

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in water to a concentration of 0.1-1.0 mg/mL. The solution can then be diluted into other aqueous buffers.

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